Predictors of health-related quality of life in Chinese patients receiving treatment for neovascular age-related macular degeneration: a prospective longitudinal study

BMC Ophthalmology
Wei BianShiying Li

Abstract

Age-related macular degeneration (AMD) is currently the leading cause of irreversible visual impairment in developed countries and seriously affects the health-related quality of life (HRQoL) of patients. However, the majority of the research in this area employs cross-sectional design; longitudinal research investigating changes in HRQoL and influencing factors is limited. The aim of this study was to use a longitudinal study design to investigate descriptive trends in HRQoL and their predictive factors in Chinese AMD patients receiving treatment with vascular endothelial growth factor inhibitors (anti-VEGF) at baseline and follow-ups. In a sample of 142 AMD patients from the outpatient clinic of the Southwest Eye Hospital, a tertiary major hospital in the southwest of China, each patient completed a self-administered questionnaire assessing demographics, clinical features, HRQoL, depression, anxiety, coping style, social support, and self-efficacy at baseline and at 1-, 3-, 6-, and 12-month follow-up appointments. The total score of HRQoL fluctuated, with the highest score at the 6-month follow-up and the lowest score at baseline. Multivariable linear regression showed the predictors of HRQoL are best-corrected visual acuity ...Continue Reading

References

Aug 1, 1981·American Journal of Community Psychology·B L Wilcox
Mar 29, 2007·Investigative Ophthalmology & Visual Science·Albert AugustinGilles Berdeaux
May 22, 2007·Progress in Retinal and Eye Research·Ursula M Schmidt-Erfurth, Christian Pruente
Jun 14, 2008·The New England Journal of Medicine·Rama D JagerJoan W Miller
Sep 2, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James E HerndonElectra D Paskett
Nov 5, 2008·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Chong-Wen WangHui-Yu Jin
Apr 7, 2010·Disability and Rehabilitation·Gwyneth ReesEcosse Lamoureux
Aug 12, 2010·Japanese Journal of Ophthalmology·Jinhyun KimHa Kyoung Kim
Feb 2, 2011·Investigative Ophthalmology & Visual Science·Peggy OrrNeil M Bressler
Jun 18, 2011·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Remy Sheena MathewMichele C Madigan
Oct 23, 2012·Ophthalmology·Jeffrey S HeierUNKNOWN VIEW 1 and VIEW 2 Study Groups
Apr 29, 2014·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Barbara Ryan
Jul 1, 2014·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Christine McCloudKonrad Pesudovs
Jun 13, 2015·Investigative Ophthalmology & Visual Science·Bonnie A SturrockGwyneth Rees
Aug 19, 2015·Cancer Nursing·Changrong Yuan
Sep 5, 2015·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Emilie MatamorosNicolas Leveziel
Sep 27, 2016·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jyoti KhadkaKonrad Pesudovs
Aug 23, 2015·European Journal of Ageing·Jiri MudrakSteriani Elavsky

❮ Previous
Next ❯

Citations

Nov 3, 2020·PharmacoEconomics·Ron D Hays, Peter M Fayers

❮ Previous
Next ❯

Software Mentioned

Statistical Package for the Social Sciences ( SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.