PMID: 9166021Apr 1, 1997Paper

Predictors of hypoxaemia in hospital admissions with acute lower respiratory tract infection in a developing country

Archives of Disease in Childhood
M W WeberE K Mulholland

Abstract

Since oxygen has to be given to most children in developing countries on the basis of clinical signs without performing blood gas analyses, possible clinical predictors of hypoxaemia were studied. Sixty nine children between the ages of 2 months and 5 years admitted to hospital with acute lower respiratory tract infection and an oxygen saturation (Sao2) < 90% were compared with 67 children matched for age and diagnosis from the same referral hospital with an Sao2 of 90% or above (control group 1), and 44 unreferred children admitted to a secondary care hospital with acute lower respiratory infection (control group 2). Using multiple logistic regression analysis, sleepiness, arousal, quality of cry, cyanosis, head nodding, decreased air entry, nasal flaring, and upper arm circumference were found to be independent predictors of hypoxaemia on comparison of the cases with control group 1. Using a simple model of cyanosis or head nodding or not crying, the sensitivity to predict hypoxaemia was 59%, and the specificity 94% and 93% compared to control groups 1 and 2, respectively; 80% of the children with an Sao2 < 80% were identified by the combination of these signs. Over half of the children with hypoxaemia could be identified wit...Continue Reading

References

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Citations

Sep 29, 2006·Indian Journal of Pediatrics·Sudha BasnetChitra Kumar Gurung
Feb 1, 2007·Indian Journal of Pediatrics·Bhavneet BhartiVandna Verma
Apr 16, 1998·The Pediatric Infectious Disease Journal·M W WeberE K Mulholland
May 1, 2007·The Pediatric Infectious Disease Journal·Philip Ayieko, Mike English
Jun 28, 2006·Pediatric Emergency Care·James Choi, Ilene Claudius
Jan 12, 2000·Archives of Disease in Childhood·V T RajeshS Kataria
Jul 3, 1999·BMJ : British Medical Journal·P BrettleS Robb
Apr 29, 2011·BMC Public Health·Alastair G CattoHarry Campbell
Jun 25, 2009·Bulletin of the World Health Organization·Michael K MwanikiJames A Berkley
Dec 13, 2012·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·M DaraUNKNOWN International Union Against Tuberculosis and Lung Disease
Sep 26, 2013·Transactions of the Royal Society of Tropical Medicine and Hygiene·Adebola E OrimadegunShannon S Carson
Apr 16, 2013·Transactions of the Royal Society of Tropical Medicine and Hygiene·Eric D McCollumNorman Lufesi
Aug 20, 2009·Annals of Tropical Paediatrics·T DukeB Frey
Jul 21, 2015·Pediatrics International : Official Journal of the Japan Pediatric Society·Pinar UygurGulnur Tokuc
Aug 14, 2013·The Journal of Emergency Medicine·Payal ModiAdam C Levine
Aug 25, 2009·Medical Hypotheses·Mark Changizi, Kevin Rio
Mar 28, 2009·The Lancet Infectious Diseases·Rami SubhiUNKNOWN Hypoxaemia in Developing Countries Study Group
Mar 24, 2006·Tropical Medicine & International Health : TM & IH·Sonja JungeMartin W Weber
Sep 29, 2011·Tropical Medicine & International Health : TM & IH·Mohammod J ChistiMohammed A Salam
May 18, 1999·Lancet·M W Weber, E K Mulholland
Apr 9, 2005·Annals of Tropical Paediatrics·Moses LamanNakapi Tefuarani
May 20, 2006·Annals of Tropical Paediatrics·S BalasubramanianG H Dinesh Chand
Dec 11, 2014·The Cochrane Database of Systematic Reviews·Maria Ximena Rojas-ReyesLaura Patricia Charry-Anzola
Jul 2, 2020·International Journal of Environmental Research and Public Health·Sunil Kumar KasundriyaAshish Pathak
Apr 9, 2020·Experimental and Therapeutic Medicine·Lun Qin LiuHai Yun Yao
Jul 24, 2014·Archives of Disease in Childhood·Trevor Duke
Mar 29, 2021·Resuscitation·Patrick Van de VoordeIan Maconochie
Jun 8, 2021·Notfall & Rettungsmedizin·Patrick Van de VoordeIan Maconochie

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