The Catheter Ablation Registry was the first international, multicenter, prospective study of the safety and efficacy of catheter ablation. From August 1987 through March 1990, the study comprised 136 patients in whom only DC energy was used in attempted production of third-degree atrioventricular block to treat uncontrollable supraventricular tachycardias. Eight patients died during hospitalization for ablation. In seven (5.1%), the ablation may have contributed to their deaths. Causes of death included ventricular fibrillation (five patients, three with polymorphic ventricular tachycardia), progressive heart failure (one patient), and respiratory failure (two patients, one dying after resuscitation from ventricular fibrillation). Compared with survivors, patients who died were more likely to have had prior aborted sudden death (38% versus 2%, p less than 0.05), congestive heart failure (88% versus 22%, p less than 0.001), cardiomyopathy (50% versus 16%, p less than 0.05), lower baseline systolic blood pressure (106 versus 138 mm Hg, p less than 0.001), prolonged baseline and postablation corrected QT interval (p less than 0.01), and markedly reduced ejection fraction (27% versus 52%, p less than 0.001). Ablation successfully ...Continue Reading
Associated Clinical Trials
Sudden death in hemochromatosis after closed-chest catheter ablation of the atrioventricular junction
Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care
Catheter ablation of the atrioventricular junction: a report of the percutaneous mapping and ablation registry
Catheter-induced ablation of the atrioventricular junction to control refractory supraventricular arrhythmias
A prospective randomized comparison of direct current and radiofrequency ablation of the atrioventricular junction
Atrial fibrillation: current understandings and research imperatives. The National Heart, Lung, and Blood Institute Working Group on Atrial Fibrillation
Catheter ablation for cardiac arrhythmias: clinical applications, personnel and facilities. American College of Cardiology Cardiovascular Technology Assessment Committee
Guidelines for clinical intracardiac electrophysiological and catheter ablation procedures. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Clinical Intracardiac Electrophysiologic and Catheter Ablation Procedures), developed in collaboration with the North American Society of Pacing and Electrophysiology
Increased sympathetic activity after atrioventricular junction ablation in patients with chronic atrial fibrillation
American College of Cardiology/American Heart Association clinical competence statement on invasive electrophysiology studies, catheter ablation, and cardioversion. A report of the American College of Cardiology/American Heart Association/American College of Physicians--American Society of Internal Medicine Task Force on clinical competence
ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. A Report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation): developed in Collaboration With the North American Society of Pacing and Electrophysiology
Sudden death after radiofrequency ablation of the atrioventricular node in patients with atrial fibrillation
Radiofrequency catheter modification of atrioventricular conduction to control the ventricular rate during atrial fibrillation
Assessment of left ventricular function after radiofrequency and direct current atrioventricular node ablation
Catheter ablation for cardiac arrhythmias, personnel, and facilities. North American Society of Pacing and Electrophysiology Ad Hoc Committee on Catheter Ablation
Effects on cardiac performance of atrioventricular node catheter ablation using radiofrequency current for drug-refractory atrial arrhythmias
Bradycardia dependent QT prolongation and ventricular fibrillation following catheter ablation of the atrioventricular junction with radiofrequency energy
Long-term survival after closed-chest His-bundle ablation with DC shock for supraventricular arrhythmias: a 10-year experience with 317 consecutive patients
Cellular electrophysiological changes induced in vitro by radiofrequency current: comparison with electrical ablation
NASPE/ACC/AHA/ESC medical/scientific statement special report--clinical investigation of antiarrhythmic devices: a statement for healthcare professionals from a Joint Task Force of the North American Society of Pacing and Electrophysiology, the American College of Cardiology, the American Heart Association, and the Working Groups on Arrhythmias and Cardiac Pacing of the European Society of Cardiology
Myocardial injury induced by radiofrequency and low energy ablation: a quantitative study of CK isoforms, CK-MB, and troponin-T concentrations
Long-term follow-up after atrioventricular nodal ablation and pacing: low incidence of sudden cardiac death
Transient QT prolongation with torsades de pointes tachycardia after ablation of permanent junctional reciprocating tachycardia
Catheter ablation for cardiac arrhythmias, personnel, and facilities. The NASPE Ad Hoc Committee on Catheter Ablation
Comparison of catheter ablation using direct current energy versus radiofrequency: observations in 147 patients with supraventricular tachyarrhythmias
Catheter ablation for successful management of left posterior fascicular tachycardia: an approach guided by recording of fascicular potentials
Torsade de pointes secondary to d,l-sotalol after catheter ablation of incessant atrioventricular reentrant tachycardia--evidence for a significant contribution of the "cardiac memory"
Atrioventricular junction ablation and pacemaker implantation for heart failure associated with atrial fibrillation: potential issues and therapies in the setting of acute heart failure syndrome
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society
Transient proarrhythmic state following atrioventricular junction radiofrequency ablation: pathophysiologic mechanisms and recommendations for management
An approach to ablate and pace:AV junction ablation and pacemaker implantation performed concurrently from the same venous access site
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