Predictors of in-hospital mortality after DC catheter ablation of atrioventricular junction. Results of a prospective, international, multicenter study

G T EvansM Josephson


The Catheter Ablation Registry was the first international, multicenter, prospective study of the safety and efficacy of catheter ablation. From August 1987 through March 1990, the study comprised 136 patients in whom only DC energy was used in attempted production of third-degree atrioventricular block to treat uncontrollable supraventricular tachycardias. Eight patients died during hospitalization for ablation. In seven (5.1%), the ablation may have contributed to their deaths. Causes of death included ventricular fibrillation (five patients, three with polymorphic ventricular tachycardia), progressive heart failure (one patient), and respiratory failure (two patients, one dying after resuscitation from ventricular fibrillation). Compared with survivors, patients who died were more likely to have had prior aborted sudden death (38% versus 2%, p less than 0.05), congestive heart failure (88% versus 22%, p less than 0.001), cardiomyopathy (50% versus 16%, p less than 0.05), lower baseline systolic blood pressure (106 versus 138 mm Hg, p less than 0.001), prolonged baseline and postablation corrected QT interval (p less than 0.01), and markedly reduced ejection fraction (27% versus 52%, p less than 0.001). Ablation successfully ...Continue Reading

Associated Clinical Trials


Jan 15, 1991·The American Journal of Cardiology·J J LangbergM M Scheinman
Aug 1, 1988·Pacing and Clinical Electrophysiology : PACE·S LévyJ F Leclercq
Nov 1, 1988·Pacing and Clinical Electrophysiology : PACE·G T EvansG Fontaine
Nov 1, 1989·British Heart Journal·E RowlandA Rickards
Sep 1, 1988·Progress in Cardiovascular Diseases·W M JackmanR Lazzara
Apr 15, 1988·The American Journal of Cardiology·R LemeryH J Wellens
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Jun 9, 1984·Lancet·A W NathanA J Camm
Oct 1, 1980·Annals of Internal Medicine·W M Smith, J J Gallagher
Jan 28, 1982·The New England Journal of Medicine·J J GallagherG Critelli
Aug 20, 1982·JAMA : the Journal of the American Medical Association·M M ScheinmanR Gonzalez

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Jul 17, 2008·Herzschrittmachertherapie & Elektrophysiologie·Damir Erkapic, Heinz-Friedrich Pitschner
Mar 1, 1993·Journal of the American College of Cardiology·J D Fisher
Jan 1, 1993·Journal of the American College of Cardiology·F MoradyS J Kalbfleisch
Sep 1, 2004·International Journal of Cardiology·Ijaz A KhanReshma C Nair
Jan 1, 1995·Progress in Cardiovascular Diseases·G K Feld
May 12, 2000·Journal of the American College of Cardiology·M M Scheinman
Jul 18, 2000·Journal of the American College of Cardiology·M H HamdanM L Smith
Jul 10, 2002·Journal of the American College of Cardiology·Cevher OzcanWin-Kuang Shen
Jun 20, 2001·Progress in Pediatric Cardiology·D P. Chan
May 27, 2003·Pacing and Clinical Electrophysiology : PACE·Yoshihide TakahashiUNKNOWN Ablation and Pacing Therapy Working Group
Feb 1, 1996·Australian and New Zealand Journal of Medicine·J WongR J Warren
Dec 1, 1992·Pacing and Clinical Electrophysiology : PACE·B OlshanskyR J Hariman
Feb 1, 1993·Pacing and Clinical Electrophysiology : PACE·F MolinR Nadeau
Jan 1, 1995·Pacing and Clinical Electrophysiology : PACE·M M Scheinman
Sep 1, 1995·Pacing and Clinical Electrophysiology : PACE·S M JensenM Rosenqvist
Mar 1, 1996·Pacing and Clinical Electrophysiology : PACE·M Brignole, C Menozzi
Jan 5, 2001·Pacing and Clinical Electrophysiology : PACE·M GaspariniR Mantovan
Apr 1, 1993·Journal of Cardiovascular Electrophysiology·S GürsoyK H Kuck
Nov 17, 1998·Journal of Cardiovascular Electrophysiology·M E KrebsD P Zipes
Feb 8, 1992·Journal of Interventional Cardiology·R S Stack
Oct 15, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Benoit GhayeRobert F Dondelinger
Sep 1, 2012·Cardiac Electrophysiology Clinics·Alexandru B Chicos, Bradley P Knight
Jan 22, 2011·Pacing and Clinical Electrophysiology : PACE·Jane C CaldwellClifford J Garratt
Sep 1, 1993·American Heart Journal·M D Lesh
Apr 1, 1993·The West Virginia Medical Journal·R McCowan

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