Predictors of Lifestyle Intervention Attrition or Weight Loss Success in Women with Polycystic Ovary Syndrome Who Are Overweight or Obese

Nutrients
Lisa J MoranRobert J Norman

Abstract

Background/objectives: Polycystic ovary syndrome (PCOS) is a common condition in reproductive-aged women. Weight management is a first-line treatment for PCOS according to international evidence-based guidelines. However, the factors associated with attrition or success in weight loss interventions are not known for women with PCOS. The objective of this study was to identify characteristics associated with attrition and weight loss success in women with PCOS and overweight or obesity undergoing weight loss interventions. Methods: Four randomised controlled clinical weight loss trials comprising energy restricted diets and/or exercise interventions of 2⁻8 months duration. The interventions were conducted over 2001⁻2007 in outpatient clinical research centres with n = 221 premenopausal women with PCOS and overweight/obesity recruited through community advertisement. The main outcome measures were attrition and ≥5% weight loss at 2 months and study completion. Results: Weight loss was 5.7 ± 2.9 kg at 2 months and 7.4 ± 5.3 kg after study completion (p < 0.001). Attrition was 47.1% and ≥5% weight loss occurred in 62.5% and 62.7% of women at 2 months and study completion respectively. Baseline depressive symptoms (OR 1.07 95% CI 0....Continue Reading

References

Jan 1, 1990·International Journal of Psychiatry in Medicine·J M ZichT K Greenfield
Oct 16, 1999·The Journal of Clinical Endocrinology and Metabolism·A VermeulenJ M Kaufman
Feb 8, 2002·The New England Journal of Medicine·William C KnowlerUNKNOWN Diabetes Prevention Program Research Group
Feb 8, 2003·The Journal of Clinical Endocrinology and Metabolism·L J MoranR J Norman
Dec 23, 2003·Human Reproduction·UNKNOWN Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group
Jul 9, 2004·The Journal of Clinical Endocrinology and Metabolism·L J MoranR J Norman
Jan 6, 2005·JAMA : the Journal of the American Medical Association·Michael L DansingerErnst J Schaefer
Mar 1, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A TolinoC L De Falco
Jul 11, 2006·The American Journal of Clinical Nutrition·Lisa J MoranRobert J Norman
May 17, 2007·The Journal of Clinical Endocrinology and Metabolism·Lisa J MoranRobert J Norman
Feb 18, 2009·The International Journal of Behavioral Nutrition and Physical Activity·Jessica Gokee-LaroseRena R Wing
Sep 30, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J Gokee-LaRoseR R Wing
Oct 28, 2009·Journal of the American Dietetic Association·Siew S LimManny Noakes
Sep 14, 2010·Human Reproduction Update·Cheryce L HarrisonHelena J Teede
May 18, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·S M SomersetK Markwell
Jul 8, 2011·The Cochrane Database of Systematic Reviews·Lisa J MoranHelena J Teede
Aug 6, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·I MoroshkoP O'Brien
Aug 17, 2012·The Cochrane Database of Systematic Reviews·L Susan WielandKarina W Davidson
Sep 26, 2012·The Journal of Clinical Endocrinology and Metabolism·Claudia MazzeschiPierpaolo De Feo
Feb 20, 2013·Journal of the Academy of Nutrition and Dietetics·Lisa J MoranHelena J Teede
Aug 17, 2017·International Journal of Environmental Research and Public Health·Alice W Y LeungJean Woo

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Citations

Nov 18, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Sakshi ChopraAmit Kumar
Nov 20, 2020·The Journal of Clinical Endocrinology and Metabolism·Kathleen M HoegerTerhi Piltonen
Jan 28, 2021·Nutrients·Ana Cutillas-TolínAlberto M Torres-Cantero
Mar 16, 2021·Expert Review of Endocrinology & Metabolism·Basak Ozgen Saydam, Bulent Okan Yildiz
May 28, 2021·Current Obesity Reports·Jaime M MooreMelanie Cree-Green

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