Predictors of medication adherence among patients with severe psychiatric disorders: findings from the baseline assessment of a randomized controlled trial (Tecla)

BMC Psychiatry
Ulrike StentzelHans-Jörgen Grabe

Abstract

Schizophrenia and bipolar disorder are characterized by a high disease burden. Antipsychotic medication is an essential part of the treatment. However, non-adherence is a major problem. Our aim was to examine potential determinants of non-adherence for patients with severe mental disorders. Baseline data of the study "Post stationary telemedical care of patients with severe psychiatric disorders" (Tecla) were used. Medication adherence was assessed with the Medication Adherence Report Scale German version (MARS-D). A logistic regression was calculated with age, sex, education, employment status, level of global functioning, social support and intake of typical and atypical antipsychotics as predictors. N = 127 participants were included in the analysis (n = 73 men, mean age 42 years). The mean MARS-D Score was 23.4 (SD 2.5). The most common reason for non-adherence was forgetting to take the medicine. Significant positive determinants for adherence were older age (OR 1.02, 95% CI 1.011-1.024, p < 0.0001), being employed (OR 2.46, 95% CI 1.893-3.206, p < 0.0001), higher level of global functioning (overall measure of how patients are doing) (OR 1.02, 95% CI 1.012-1.028, p < 0.0001), having social support (OR 1.02, 95% CI 1.013-1...Continue Reading

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Citations

Jun 21, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Azita AlipourPuja Baldev Patel
Nov 2, 2018·European Psychiatry : the Journal of the Association of European Psychiatrists·Christopher A LovejoyMahiben Maruthappu
Apr 10, 2021·International Journal of Clinical Pharmacy·Irene A KretchyGrace Owusu Aboagye
Aug 5, 2021·Patient Preference and Adherence·Heather L WheatMary A Dolansky
Aug 12, 2021·Drug Design, Development and Therapy·Tao XiaoYuguan Wen
Aug 28, 2021·International Journal of Environmental Research and Public Health·Carl B RothChristian G Huber

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Software Mentioned

MARS
SAS
Tecla

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