Abstract
The purpose of this study was to test the hypothesis that multivessel fetal Doppler imaging provides enhanced prediction of necrotizing enterocolitis (NEC) in preterm placental insufficiency. Placental-based growth-restricted fetuses (abdominal circumference <5%, abnormal umbilical artery [UA] Doppler imaging) were examined. UA, middle cerebral artery, ductus venosus, and umbilical vein (UV) were evaluated prenatally and were assessed for their ability to predict NEC in neonates who were delivered at <37 weeks of gestation. Thirty-nine of 404 neonates (9.7%) experienced NEC. Among these, the mortality rate was 15.4% (6/39 neonates; odds ratio, 2.7; 95% CI, 1.03-7.11). NEC cases had higher UA Doppler indices prenatally (P = .023), lower gestational ages and birthweight at delivery (P < .0001, respectively), 5-minute Apgar scores of <7, and higher umbilical cord artery base deficit (P < .01, respectively). NEC was more likely after prenatal UV pulsations (odds ratio, 2.4; 95% CI, 1.13-5.14; P = .028) and severe cardiovascular abnormality (composite variable incorporating UA- absent or reversed end diastolic velocity, absent or reversed ductus venosus a-wave, or UV pulsations; odds ratio, 2.1; 95% CI, 1.06-4.05; P = .029) Logistic...Continue Reading
References
Jul 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·R C CoombsA S McNeish
Mar 1, 1992·Obstetrics and Gynecology·D GramelliniA Merialdi
Jan 3, 1987·British Medical Journal·G A HackettJ M Pearce
Feb 1, 1983·European Journal of Obstetrics, Gynecology, and Reproductive Biology·T K EskesP C Houx
Mar 1, 1994·Archives of Disease in Childhood. Fetal and Neonatal Edition·M McDonnellP L Hope
Mar 1, 1993·Clinical Obstetrics and Gynecology·A R Gregg, C P Weiner
Jan 29, 2000·American Journal of Obstetrics and Gynecology·I M BernsteinA Golan
Apr 20, 2000·Acta Paediatrica·E Robel-TilligR Faber
Feb 13, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A A BaschatC R Harman
Feb 13, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E SivanR Achiron
Mar 10, 2001·Journal of Perinatal Medicine·K Maruyama, T Koizumi
Jul 9, 2002·Obstetrics and Gynecology·Reuwen AchironZeev Rotstein
Jul 19, 2002·Journal of Perinatal Medicine·Przemyslaw KorszunSaemundur Gudmundsson
Jun 26, 2003·American Journal of Obstetrics and Gynecology·William M Gilbert, Beate Danielsen
Mar 6, 2004·Seminars in Neonatology : SN·Jane S Lee, Richard A Polin
Apr 3, 2004·Seminars in Perinatology·Ahmet A Baschat, Kurt Hecher
Aug 25, 2004·Clinics in Perinatology·Rivka H Regev, Brian Reichman
Sep 17, 2004·Pediatric Radiology·Eva Robel-TilligChristoph Vogtmann
Sep 24, 2004·BJOG : an International Journal of Obstetrics and Gynaecology·Ahmet Alexander Baschat
Apr 9, 2005·Journal of Paediatrics and Child Health·Melissa LuigUNKNOWN NSW & ACT NICUS Group
May 25, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J HartungR Chaoui
Mar 28, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A A Baschat
Nov 3, 2006·Pediatrics·Edile M MurdochStephen T Kempley
Dec 6, 2006·Pediatrics·Jeff PietzSudhir Ken Mehta
Feb 3, 2007·Obstetrics and Gynecology·Ahmet A BaschatChris R Harman
Dec 17, 2009·American Journal of Perinatology·Paraskevi KaragianniNikolaos Nikolaidis
Citations
Oct 3, 2009·Taiwanese Journal of Obstetrics & Gynecology·Kuo-Gon WangYi-Yung Chen
Apr 4, 2012·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Sheila M GephartMelissa D Halpern
May 15, 2013·Italian Journal of Pediatrics·Giovanni BaroneEnrico Zecca
Dec 15, 2010·Pathology Research International·Laure DixMaria-Chiara Osterheld
Jan 29, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·R SinghD M Kent
Aug 28, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Melissa I MarchSarosh Rana
Jul 27, 2012·Early Human Development·Merih CetinkayaNilgun Koksal
Mar 13, 2012·The Journal of Nutritional Biochemistry·Jean-Paul LallèsJean-Pierre Segain
Mar 11, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·H L TorranceG H A Visser
Dec 23, 2011·American Journal of Obstetrics and Gynecology·Marie-Josée RaboissonJean-Claude Fouron
Jan 16, 2013·Neonatal Network : NN·Erin Geary
Mar 18, 2017·Journal of Neonatal-perinatal Medicine·M F AhamedT Havranek
Apr 24, 2017·American Journal of Obstetrics and Gynecology·Malgorzata MlynarczykAlfred Z Abuhamad
Oct 10, 2009·Pediatric Research·Lianqiang ChePer T Sangild
Jun 20, 2018·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A Conde-AgudeloA T Papageorghiou
Oct 3, 2019·NeoReviews·Nadia Narendran, Kamran Yusuf
Apr 2, 2011·Current Opinion in Infectious Diseases·Jessie A MorganWilliam McGuire
Jun 26, 2020·Animals : an Open Access Journal From MDPI·Maria WieseCharlotte Amdi
Nov 28, 2015·BMC Research Notes·Ilze MeldereZane Abola
Dec 6, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mohamed Abdelmaaboud, Abdelbaset Mohammed
Dec 12, 2018·European Journal of Nutrition·Hao ZhangTian Wang
May 20, 2020·European Journal of Pediatrics·Pradhan RinaDezhi Mu
Apr 4, 2017·Journal of Tropical Pediatrics·Vishal Vishnu TewariGirish Gupta
Nov 15, 2018·International Journal of Environmental Research and Public Health·Claudine IrlesEstibalitz Laresgoiti Servitje
Apr 16, 2017·BMC Pediatrics·Noor SamuelsMarijn J Vermeulen
Mar 15, 2020·Scientific Reports·Jeik ByunSung-Eun Jung
May 9, 2014·Paediatrics and International Child Health·Peter Angura, Sithembiso Velaphi
Sep 1, 2017·The Journal of Reproduction and Development·Chao WangTian Wang
Apr 3, 2019·Pediatric Quality & Safety·Thomas MurphyJesse Bender
Jan 28, 2021·Nutrients·Laura MoschinoGiovanna Verlato
Jun 10, 2021·Global Pediatric Health·Sitotaw Molla MekonnenAddisu Dabi Wake