Predictors of neurological outcomes after successful extracorporeal cardiopulmonary resuscitation

BMC Anesthesiology
Jeong-Am RyuJi-Hyuk Yang

Abstract

Extracorporeal cardiopulmonary resuscitation (ECPR) refers to use of extracorporeal membrane oxygenation (ECMO) in cardiopulmonary arrest. Although ECPR can increase survival rates after cardiac arrest, it can also result in poor post-resuscitation neurological status. Thus, we investigated predictors of good neurological outcomes after successful ECPR. A total of 227 patients underwent ECPR from May 2004 to June 2013 at Samsung Medical Center. Successful ECPR was defined as survival more than 24 hours after ECPR. Neurological outcomes were assessed at discharge using the Glasgow-Pittsburgh Cerebral Performance Categories scale (CPC). CPC 1 and 2 were classified as good and CPC 3 to 5 were classified as poor neurological outcomes. Excluded were 22 patients who did not survive more than 24 hours after ECPR and 90 patients who died from unknown causes or causes other than brain death or whose neurological status could not be assessed at discharge. Multiple logistic regression analysis was used to identify independent predictors of neurological outcomes. Included were 115 patients with a mean age of 58 (range 45-66) years and 80 men (70%). Cardiopulmonary resuscitation (CPR) was performed at non-hospital sites for 19 (17%) patient...Continue Reading

References

Oct 1, 1992·Stroke; a Journal of Cerebral Circulation·K Korosue, R C Heros
Aug 5, 1999·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·J G YoungerR H Bartlett
Sep 3, 2004·Medicine·Andreas KliegelAnton N Laggner
May 20, 2009·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Cindy S BarrettRavi R Thiagarajan
Jan 20, 2011·Critical Care : the Official Journal of the Critical Care Forum·Morgan Le GuenOlivier Langeron
Jun 7, 2011·The American Journal of Emergency Medicine·UNKNOWN SOS-KANTO study group
Dec 23, 2011·Critical Care : the Official Journal of the Critical Care Forum·Luciano GattinoniThomas Langer
Sep 11, 2012·Lancet·Zachary D GoldbergerUNKNOWN American Heart Association Get With The Guidelines—Resuscitation (formerly National Registry of Cardiopulmonary Resuscitati
Jan 24, 2013·Circulation·Renée I MatosUNKNOWN American Heart Association’s Get With The Guidelines–Resuscitation (Formerly the National Registry of Cardiopulmonary Resusc
Apr 19, 2013·Critical Care : the Official Journal of the Critical Care Forum·Cecile AubronVince Pellegrino
Jul 25, 2013·Critical Care : the Official Journal of the Critical Care Forum·T W LindnerE Søreide
Jan 29, 2014·The American Journal of Emergency Medicine·Keigo SawamotoEichi Narimatsu
Mar 15, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yang Hyun ChoDuk-Kyung Kim
Aug 21, 2014·The New England Journal of Medicine·Michael R DeBaunJames F Casella
Jan 1, 2015·The New England Journal of Medicine·Lars B HolstAnders Perner
Jan 1, 2015·The New England Journal of Medicine·Elena Gordillo-EscobarSantiago R Leal-Noval

❮ Previous
Next ❯

Citations

Dec 18, 2015·Critical Care : the Official Journal of the Critical Care Forum·Jarrod M MosierDaniel W Spaite
Jun 24, 2017·Critical Care Medicine·Régis BronchardOlivier Bastien
Mar 31, 2018·Artificial Organs·Chang-Chyi JenqYung-Chang Chen
Aug 26, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Dirk PabstChristoph E Brehm
Nov 14, 2018·Critical Care Medicine·Kathleen L MeertUNKNOWN Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA) Trial Investigators
Nov 8, 2018·The Korean Journal of Thoracic and Cardiovascular Surgery·Wonho Chang
Oct 11, 2019·Critical Care Medicine·Sung-Min ChoRomergryko G Geocadin
Nov 24, 2018·Critical Care : the Official Journal of the Critical Care Forum·Jeong-Am RyuJeong Hoon Yang
Mar 25, 2020·Journal of the American Heart Association·Akihiko InoueYasuhiro Kuroda
Aug 27, 2015·The Journal of Trauma and Acute Care Surgery·Sarah B Murthi, Thomas M Scalea
Aug 5, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Marinella MarinoniAdriano Peris
Jun 4, 2019·Emergency Medicine Australasia : EMA·Jeong Ho ParkKi Jeong Hong
Jan 26, 2017·Critical Care : the Official Journal of the Critical Care Forum·Jeong-Am RyuJeong Hoon Yang
Nov 17, 2016·Intensive Care Medicine·Anders Aneman, Peter Macdonald
Jun 25, 2020·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Fu-Yuan SiaoHsu-Hen Yen
Jan 16, 2020·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Xi ChenYue Yuan
Apr 3, 2020·Revista brasileira de enfermagem·Gislaine Rodrigues NakasatoCamila Takao Lopes
Jul 6, 2021·Resuscitation Plus·Tyler E Klee, Karl B Kern
Aug 17, 2021·Journal of Pediatric Intensive Care·Rebecca Anderson de la LlanaAdrian Christian Mattke

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.