Predictors of outcome in cognitive and behavioural interventions for irritable bowel syndrome. A meta-analysis

Journal of Gastrointestinal and Liver Diseases : JGLD
Mădălina RaduDan L Dumitrascu

Abstract

Cognitive behavioural therapy (CBT) has small to medium effects in alleviating emotional distress and psychosomatic symptoms in irritable bowel syndrome (IBS). However, the mechanism through which CBT exerts its effects is less studied. Mediation analysis examines the extent to which intermediate variables explain the effect of the intervention on outcomes. The meta-analysis aims to identify and assess the impact of CBT mediators identified in previous research on IBS. An extensive search of studies investigating the effects of CBT for IBS published before January 2018 was conducted. A total of 699 studies were identified through database search and 6 studies including data from 638 patients were analysed. The selected studies had to clearly define the CBT intervention, include IBS patients, report sufficient data to allow calculation of effect sizes and provide a clear mediation analysis of one or several variables on the outcome. The total effect of CBT was significant for both categories of outcomes (i.e. IBS symptom severity and psychosocial distress), with a low-to-moderate effect on psychosocial distress (r=0.222) and a medium-to-large effect on IBS symptom severity (r=0.413). In fact, the total effect of CBT on IBS sympt...Continue Reading

Citations

Oct 22, 2019·Therapeutic Advances in Gastroenterology·David J Cangemi, Brian E Lacy
Nov 28, 2020·World Journal of Gastroenterology : WJG·Yun-Kai DaiLing Hu

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