Predictors of Outcomes in Diabetic Foot Osteomyelitis Treated Initially With Conservative (Nonsurgical) Medical Management: A Retrospective Study

The International Journal of Lower Extremity Wounds
Paul ZeunKetan Dhatariya

Abstract

The optimal way to manage diabetic foot osteomyelitis remains uncertain, with debate in the literature as to whether it should be managed conservatively (ie, nonsurgically) or surgically. We aimed to identify clinical variables that influence outcomes of nonsurgical management in diabetic foot osteomyelitis. We conducted a retrospective study of consecutive patients with diabetes presenting to a tertiary center between 2007 and 2011 with foot osteomyelitis initially treated with nonsurgical management. Remission was defined as wound healing with no clinical or radiological signs of osteomyelitis at the initial or contiguous sites 12 months after clinical and/or radiological resolution. Nine demographic and clinical variables including osteomyelitis site and presence of foot pulses were analyzed. We identified 100 cases, of which 85 fulfilled the criteria for analysis. After a 12-month follow-up period, 54 (63.5%) had achieved remission with nonsurgical management alone with a median (interquartile range) duration of antibiotic treatment of 10.8 (10.1) weeks. Of these, 14 (26%) were admitted for intravenous antibiotics. The absence of pedal pulses in the affected foot (n = 34) was associated with a significantly longer duration ...Continue Reading

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Citations

Mar 17, 2016·The International Journal of Lower Extremity Wounds·Eran TamirGabriel Agar
Nov 18, 2017·BMC Musculoskeletal Disorders·Martin BerliCharlotte Baltin
Apr 7, 2019·Diabetes/metabolism Research and Reviews·Pinar SenBusra Emir
May 29, 2019·Journal of the American Podiatric Medical Association·Whitney MillerHeather Young
Dec 19, 2015·The International Journal of Lower Extremity Wounds·Kittipan Rerkasem, Raj Mani
Sep 12, 2017·International Journal of Clinical Practice·Nicholas D BarwellUNKNOWN Scottish Diabetes Foot Action Group
Dec 13, 2017·Expert Review of Anti-infective Therapy·Javier Aragón-Sánchez, Benjamin A Lipsky
Apr 4, 2021·Journal of Clinical Medicine·Aroa Tardáguila-GarcíaJosé Luis Lázaro-Martínez
Apr 26, 2017·Endocrinología, Diabetes Y Nutrición·José Luis Lázaro-MartínezJosé Luis García-Klepzig
Nov 4, 2020·Journal of the American Podiatric Medical Association·Peter A CrisologoLawrence A Lavery

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Methods Mentioned

BETA
amputations
amputation
biopsy
biopsies
X-ray

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SPSS

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