Predictors of perinatal survival in a cohort of pregnancies with severe oligohydramnios due to premature rupture of membranes at <26 weeks managed with serial amnioinfusions

European Journal of Obstetrics, Gynecology, and Reproductive Biology
A LocatelliP Vergani

Abstract

To evaluate whether successful amnioinfusion is an independent predictor of perinatal survival in a cohort of cases with extreme and persistent oligohydramnios due to preterm premature rupture of membranes (pPROM) who reached viability and were managed with serial amnioinfusions. We included all consecutive singleton pregnancies with pPROM at <26 weeks and oligohydramnios lasting >4 days between 1/1991 and 12/2001 and who consented to undergo amnioinfusion (n=77). Women received serial transabdominal amnioinfusions in an attempt to maintain a pocket of fluid >2 cm. The procedure was deemed successful if the median deepest pocket of fluid during the latency period was >2 cm. Excluded were miscarriages (n=10), fetal deaths before viability (24 weeks) (n=15), and cases that did not develop oligohydramnios (n=17). Prenatal predictors of outcome were compared between cases who survived the perinatal period and those who did not using Wilcoxon rank-sum test, Fisher's exact test and stepwise logistic regression analysis, with a two-tailed P<0.05 considered significant. Of the 35 patients fulfilling the study criteria, 20 (57%) survived the perinatal period. Perinatal survivors had similar gestational age at pPROM (P=0.68) and at first...Continue Reading

References

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Citations

Jan 10, 2008·Taiwanese Journal of Obstetrics & Gynecology·Tian-Lun HsuChia-Yu Ou
Nov 30, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·A LocatelliC M Salafia
Mar 13, 2014·Current Opinion in Obstetrics & Gynecology·Zoltan KozinszkyNorbert Pásztor
Jan 1, 2014·Journal of Clinical Medicine·Samuel EngemiseWilliam Davies
Mar 12, 2010·Journal of Perinatology : Official Journal of the California Perinatal Association·H SoyluP S Shah
Feb 22, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Tamara Jane HunterCraig E Pennell
May 4, 2011·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·G ClericiG C Di Renzo
Jul 4, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Juliana Silva EstevesLuis Guillermo Coca Velarde
Nov 23, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D RobertsZ Alfirevic
Dec 18, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Anshuja SinglaMohammad M A Faridi
Apr 1, 2014·The Cochrane Database of Systematic Reviews·G Justus HofmeyrTheresa A Lawrie

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