Predictors of poor adherence to antidiabetic therapy in patients with type 2 diabetes: a cross-sectional study insight from Ethiopia

Diabetology & Metabolic Syndrome
Gebre Teklemariam DemozAndrew Collier

Abstract

Poor adherence to the medical regimen is a major clinical problem in the management of patients with diabetes. This study sought to investigate the level of medication adherence to antidiabetic therapy and to identify possible predictors of poor adherence. A hospital based cross-sectional study was conducted from July 2018 to June 2019 among randomly selected follow-up T2D patients at a hospital diabetes clinic. Data were collected through patient interviews, followed by medical chart review. Adherence to antidiabetic therapy that we assessed patients' responses using validated Brief Medication Questionnaire (BMQ). To identify predictors of poor medication adherence, binary logistic regression analyses were performed using SPSS version 25. Statistical significance was set at p value ≤ 0.05. Of the total 357 study participants, 25% were non-adherent to their antidiabetic therapy. Predictors statistically associated with poor adherence were; being female gender (AOR = 1.71, 95% CI 1.01-2.76), and presence of at least one diabetic complication (AOR = 2.02, 95% CI 1.02-3.22). Participants with having at least primary level of education were more likely to adhere to anti-diabetes medication (AOR = 0.42, 95% CI 0.18-0.96). The most c...Continue Reading

References

Nov 1, 1995·The Diabetes Educator·J T FitzgeraldW K Davis
Oct 8, 2003·Patient Education and Counseling·B L SvarstadC Claesson
Apr 28, 2004·Diabetes Care·Joyce A Cramer
May 24, 2005·Medical Care·Michael C SokolRobert S Epstein
Nov 14, 2006·Lancet·David Beran, John S Yudkin
Sep 12, 2008·Pharmacy World & Science : PWS·Kazeem B YusuffBonatson Y Joseph
Jul 25, 2009·Pharmacy World & Science : PWS·Bob W van Roozendaal, Ines Krass
Jun 10, 2010·Korean Diabetes Journal·Kyung-Ae ParkSung-Taek Hyun
Feb 10, 2012·The Diabetes Educator·Genee R BaileyNathan D Pope
Mar 1, 2012·North American Journal of Medical Sciences·Nasir T WabeSadikalmahdi Hussein
Mar 27, 2012·The Diabetes Educator·Antoinette M SchoenthalerWalter F Stewart
Jan 18, 2014·Current Medical Research and Opinion·Sarah CliffordKarin S Coyne
Feb 1, 2014·BMC Public Health·Solomon Mekonnen AbebeAbebayehu Assefa
May 17, 2014·SpringerPlus·Solomon Mekonnen AbebeAlemayehu Worku
May 14, 2016·International Journal of Environmental Research and Public Health·Abdullah Al HamidMaisoon Ghaleb

❮ Previous
Next ❯

Citations

Jan 12, 2021·Clinical Medicine Insights. Endocrinology and Diabetes·Girma DegefaAgete Tadewos Hirigo
Oct 17, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Adugna OlumaEba Abdissa
Aug 28, 2021·International Journal of Environmental Research and Public Health·Iwona BonikowskaIzabella Uchmanowicz

❮ Previous
Next ❯

Software Mentioned

SPSS
EpiData Manager
EpiData Entry Client

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.