Predictors of suicide attempt in patients with obsessive-compulsive disorder: an exploratory study with machine learning analysis

Psychological Medicine
Neusa Aita AgneYgor A Ferrão

Abstract

Patients with obsessive-compulsive disorder (OCD) are at increased risk for suicide attempt (SA) compared to the general population. However, the significant risk factors for SA in this population remains unclear - whether these factors are associated with the disorder itself or related to extrinsic factors, such as comorbidities and sociodemographic variables. This study aimed to identify predictors of SA in OCD patients using a machine learning algorithm. A total of 959 outpatients with OCD were included. An elastic net model was performed to recognize the predictors of SA among OCD patients, using clinical and sociodemographic variables. The prevalence of SA in our sample was 10.8%. Relevant predictors of SA founded by the elastic net algorithm were the following: previous suicide planning, previous suicide thoughts, lifetime depressive episode, and intermittent explosive disorder. Our elastic net model had a good performance and found an area under the curve of 0.95. This is the first study to evaluate risk factors for SA among OCD patients using machine learning algorithms. Our results demonstrate an accurate risk algorithm can be created using clinical and sociodemographic variables. All aspects of suicidal phenomena need...Continue Reading

References

Feb 1, 1969·Archives of General Psychiatry·D W GoodwinE Robins
Jan 1, 1996·Depression and Anxiety·E HollanderM M Weissman
Jan 31, 2003·Psychological Bulletin·Emily J OzerDaniel S Weiss
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Jun 19, 2004·European Archives of Psychiatry and Clinical Neuroscience·Jules AngstWulf Rössler
Jun 9, 2005·Archives of General Psychiatry·Ronald C KesslerEllen E Walters
Sep 17, 2005·Psychological Medicine·José M BertoloteDanuta Wasserman
May 10, 2006·European Archives of Psychiatry and Clinical Neuroscience·Raşit TükelOlcay Yazici
Jun 14, 2006·Comprehensive Psychiatry·Jane L EisenSteven A Rasmussen
Oct 16, 2007·CNS Spectrums·Albina Rodrigues TorresAron Barbosa C Guimarães
Nov 14, 2007·Acta Psychiatrica Scandinavica·S LeeR C Kessler
Dec 7, 2007·The Journal of Clinical Psychiatry·Prakash KamathThennarasu Kandavel
Oct 4, 2008·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Euripedes Constantino MiguelUNKNOWN Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders
Apr 21, 2009·Lancet·Keith Hawton, Kees van Heeringen
Nov 20, 2009·Psychiatry Research·Volkan Balci, Levent Sevincok
Jan 12, 2010·Journal of Affective Disorders·P AlonsoJ M Menchón
Jan 29, 2011·The Journal of Clinical Psychiatry·Albina R TorresEuripedes C Miguel
Jun 25, 2013·Clinical Psychology Review·Julia A DiGangiKarestan C Koenen
Apr 22, 2014·Comprehensive Psychiatry·Ryan J JacobyJonathan S Abramowitz
Jun 15, 2014·BMJ : British Medical Journal·Trisha GreenhalghUNKNOWN Evidence Based Medicine Renaissance Group
Apr 16, 2015·Clinical Psychology Review·Ioannis AngelakisMaria Panagioti
Jun 16, 2015·Psychiatric Services : a Journal of the American Psychiatric Association·Christine Leonard WestgateBradley V Watts
Jan 7, 2016·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Mark E LarsenHelen Christensen
Feb 26, 2016·Nature Neuroscience·Quentin J M HuysMichael J Frank
Jul 20, 2016·Molecular Psychiatry·L Fernández de la CruzD Mataix-Cols
Sep 9, 2016·European Psychiatry : the Journal of the Association of European Psychiatrists·P VellosoM C do Rosário
Nov 15, 2016·Psychological Bulletin·Joseph C FranklinMatthew K Nock
Feb 6, 2018·Annual Review of Clinical Psychology·Dominic B DwyerNikolaos Koutsouleris

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