Predictors of surgical site infection after open lower extremity revascularization

Journal of Vascular Surgery
Frank M DavisPeter K Henke

Abstract

Surgical site infection (SSI) after open lower extremity bypass (LEB) is a serious complication leading to an increased rate of graft failure, hospital readmission, and health care costs. This study sought to identify predictors of SSI after LEB for arterial occlusive disease and also potential modifiable factors to improve outcomes. Data from a statewide cardiovascular consortium of 35 hospitals were used to obtain demographic, procedural, and hospital risk factors for patients undergoing elective or urgent open LEB between January 2012 and June 2015. Bivariate comparisons and targeted maximum likelihood estimation were used to identify independent risk factors of SSI. Adjusted odds ratios (ORs) were calculated for patient demographics, comorbidities, operative details, and hospital-level factors. Our study population included 3033 patients who underwent 703 femoral-femoral bypasses, 1431 femoral-popliteal bypasses, and 899 femoral-distal vessel bypasses. An SSI was diagnosed in 320 patients (10.6%) ≤30 days after the index operation. Adjusted patient and procedural predictors of SSI included renal failure currently requiring dialysis (OR, 4.35; 95% confidence interval [CI], 3.45-5.47; P < .001), hypertension (OR, 4.29; 95% CI...Continue Reading

Citations

Nov 19, 2019·Vascular and Endovascular Surgery·Brandon McGuinnessMichael Stacey
Apr 28, 2020·The International Journal of Artificial Organs·Gabriele DonatiGaetano La Manna
Oct 3, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Philippe TressonAnne Long
Nov 7, 2020·Annals of Vascular Surgery·Haroon RasheedMaham Rahimi
Feb 7, 2021·Journal of Vascular Surgery·Daniel J BertgesUNKNOWN PREVENA Trial Investigators
Jan 2, 2021·Annals of Vascular Diseases·Yoshihiko TsujiYoriko Tsuji
Feb 10, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Nabil ChakféAnders Wanhainen
Jun 12, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Barend M E MeesJan Willem H C Daemen
Mar 30, 2019·Journal of Vascular Surgery·Bala RamananShirling Tsai
May 31, 2019·Journal of Vascular Surgery·Gabriele PiffarettiUNKNOWN PROPATEN Italian Registry Group

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