Predictors of trabecular bone score in school children

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
K ShawwaGhada El-Hajj Fuleihan

Abstract

Trabecular bone score (TBS) is a DXA-based tool that assesses bone texture and reflects microarchitecture. It has been shown to independently predict the risk of osteoporotic fracture in the elderly. In this study, we investigated the determinants of TBS in adolescents. TBS is a gray-level textural measurement derived from lumbar spine DXA images. It appears to be an index of bone microarchitecture that provides skeletal information additional to the standard BMD measurement and clinical risk factors. Our objectives were to characterize the relationship between TBS and both age and pubertal stages and identify other predictors in adolescents. We assessed TBS by reanalyzing spine DXA scan images obtained from 170 boys and 168 girls, age range 10-17 years, gathered at study entry and at 1 year, using TBS software. The results are from post hoc analyses obtained using data gathered from a prospective randomized vitamin D trial. Predictors of TBS were assessed using t test or Pearson's correlation and adjusted using regression analyses, as applicable. The mean age of the study population was 13.2 ± 2.1 years, similar between boys and girls. Age, height, weight, sun exposure, spine BMC and BMD, body BMC and BMD, and lean and fat mas...Continue Reading

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Citations

May 21, 2016·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M D WalkerS J Silverberg
Sep 5, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·N K HydeJ A Pasco
Jul 8, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Dimitris VlachopoulosLuis Gracia-Marco
Jul 19, 2018·The Journal of Clinical Endocrinology and Metabolism·Hanh H NguyenAmanda Vincent
Aug 2, 2018·Medicine and Science in Sports and Exercise·Dimitris VlachopoulosLuis Gracia-Marco
Mar 1, 2019·Archives of Osteoporosis·Miguel Angel GuagnelliPatricia Clark
May 13, 2020·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Mirko RehbergIbrahim Duran
Jun 30, 2019·Archives of Osteoporosis·Faezeh RastgooAminReza Amini
Aug 29, 2018·Archives of Osteoporosis·Giulia RodariC Giavoli
Oct 12, 2018·Archives of Osteoporosis·Esther Ubago-GuisadoLuis Gracia-Marco
Oct 20, 2017·Archives of Osteoporosis·Jodi N DowthwaiteT A Scerpella
Sep 25, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S SaitoH Sakakibara
Oct 22, 2020·Indian Journal of Endocrinology and Metabolism·Remya RajanThomas V Paul
Nov 16, 2020·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Yael Levy-ShragaBatia Weiss
Dec 29, 2020·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Aditi WaghAnuradha Khadilkar

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