Predictors of verbal memory decline following temporal lobe surgery

Neuro-Chirurgie
A de Vanssay-MaigneS Baudoin-Chial

Abstract

Verbal memory decline can occur after temporal lobe surgery, especially when the left dominant hemisphere is involved. This potential functional risk must be evaluated before surgery. Among all factors that have been identified by several studies, the side of surgery (left dominant) and high baseline memory performance have been found to be predictive of verbal memory decline. Other factors such as etiology, sex, age at surgery, age at seizure onset, and duration may influence memory decline, but the results are not clear. Our purpose was to identify, in our population of patients and among all risk factors, those that may be predictive of verbal memory decline. Logistic regression was used to examine the effect of each factor on the postoperative verbal memory index (WMS-R) in 101 patients who underwent a right (n=49) or left (n=52) anterior temporal lobe resection. In the group as a whole, 22 % of the patients demonstrated verbal memory decline of more than one standard deviation. The verbal memory decline was significantly related to surgery on the left side and a high level of verbal memory performance. These factors were significant predictors of decline. The other factors (etiology, sex, age at surgery, age at seizure ons...Continue Reading

References

Oct 27, 1997·Brain and Cognition·M SeidenbergF C Dohan
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Nov 23, 2006·Epilepsia·Sallie BaxendaleJohn Duncan

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Citations

Feb 26, 2016·Seizure : the Journal of the British Epilepsy Association·Hongbo JinQianwei Liu

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