Predictors of warfarin use in atrial fibrillation patients in the inpatient setting

American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions
Shuchita AgarwalDavid J Smith

Abstract

There is substantial published evidence that warfarin reduces the risk of stroke in patients with atrial fibrillation (AF). However, the current literature suggests that not all patients who could benefit from warfarin receive the drug. To evaluate patient-related demographic and clinical factors that could influence warfarin use or other anticoagulant use in hospitalized patients with AF. Retrospective observational study using claims data from the Wolters Kluwer Pharma Solutions Hospital Patient Level Database, evaluating characteristics of patients hospitalized in the US between 1 November 2003 and 31 October 2004. Hospital care. The study included 44,193 patients aged >or=40 years who were hospitalized between 1 November 2003 and 31 October 2004 and had a diagnosis of AF during hospitalization (AF did not need to be the cause of hospitalization). Use of warfarin or other anticoagulants (unfractionated heparin [UFH] or low-molecular-weight heparin [LMWH]) was evaluated. A logistic regression model was used to identify factors associated with warfarin use, international normalized ratio (INR) monitoring, or the use of anticoagulants (UFH or LMWH). In this analysis of hospitalized patients with AF in the real-world setting, ab...Continue Reading

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Citations

Apr 11, 2013·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Maria M FernandezWinghan Jacqueline Kwong
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