Predisposing and precipitating factors for delirium in a frail geriatric population

Journal of Psychosomatic Research
Jouko V LaurilaKaisu H Pitkala

Abstract

The aim of this study was to assess the possible predisposing aetiologic and short-term precipitating factors for delirium in acutely ill hospital patients with a heavy burden of comorbidities and medications. Eighty-seven consecutive patients with acute delirium admitted to a general medicine unit were thoroughly examined, and the predisposing and precipitating factors of their delirium were assessed. In this population, an average of 5.2 predisposing factors and 3.0 potential precipitating factors for delirium was revealed, meaning an average of over eight possible aetiological causes for each patient. The most common precipitating factors were infections (n=72), metabolic abnormalities (n=52), adverse drug effects (n=41), and cardiovascular events (n=38). In addition, a number of very rare conditions were diagnosed after thorough assessments. Geriatric patients with acute delirium typically present with several concomitant predisposing factors for delirium exposing them to high vulnerability for the syndrome. In most patients, a number of possible etiological causes for delirium can be identified after a careful assessment, but their true pathogenetic pathway to the syndrome is unclear.

References

Jan 1, 1991·International Psychogeriatrics·C A RossM F Folstein
Jun 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C P HughesR L Martin
Jan 1, 1982·Journal of Psychiatric Research·J A YesavageV O Leirer
Jun 1, 1980·The American Journal of Psychiatry·Z J Lipowski
Mar 20, 1996·JAMA : the Journal of the American Medical Association·S K Inouye, P A Charpentier
Apr 16, 1998·Journal of General Internal Medicine·M ElieF Bellavance
Nov 27, 1998·The American Journal of Medicine·E R MarcantonioT H Lee
Jan 23, 1999·Journal of Geriatric Psychiatry and Neurology·D J MeagherP T Trzepacz
Jan 13, 2000·International Psychogeriatrics·D B RolfsonK Rockwood
Mar 29, 2000·Archives of Internal Medicine·P G LawlorE D Bruera
Feb 7, 2001·Journal of Geriatric Psychiatry and Neurology·V CamusI Simeone
Jun 29, 2000·Archives of Internal Medicine·C BrauerA L Siu
Feb 24, 2001·Journal of the American Geriatrics Society·J T HanlonM Weinberger
Mar 14, 2002·Journal of the American Geriatrics Society·A EdlundY Gustafson
Jun 27, 2003·Dementia and Geriatric Cognitive Disorders·Jouko V LaurilaReijo S Tilvis
Feb 6, 2004·General Hospital Psychiatry·Jouko V LaurilaReijo S Tilvis
May 11, 2005·General Hospital Psychiatry·Sarah L MindenE John Orav
Mar 3, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kaisu H PitkäläReijo S Tilvis
Mar 17, 2006·The New England Journal of Medicine·Sharon K Inouye
May 10, 2007·Scandinavian Cardiovascular Journal : SCJ·Ieva NorkieneGiedrius Uzdavinys
May 12, 2007·Journal of the American Geriatrics Society·Sharon K InouyeGeorge A Kuchel
Aug 23, 2007·Journal of Geriatric Psychiatry and Neurology·Agneta EdlundYngve Gustafson

❮ Previous
Next ❯

Citations

Feb 4, 2010·International Psychogeriatrics·Sofie TängmanLillemor Lundin-Olsson
Aug 19, 2010·International Psychogeriatrics·Irene ErikssonBirgitta Olofsson
Mar 24, 2010·Palliative & Supportive Care·Tomomi WadaHideki Onishi
May 12, 2010·Clinical Interventions in Aging·B R Sommer, H H Fenn
Jul 21, 2012·Drugs & Aging·Peter C WierengaSophia E J A de Rooij
Sep 3, 2009·Case Reports in Medicine·Vikrant MittalRajesh R Tampi
Apr 10, 2014·Clinical Medicine : Journal of the Royal College of Physicians of London·Barbara C van Munster, S E de Rooij
Aug 16, 2011·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·Sheetal DhariaEricka L Breden
Feb 17, 2009·International Review of Psychiatry·Alasdair M J MacLullichDavid J Meagher
Aug 3, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Daniel H J DavisCarol Brayne
Nov 17, 2009·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Barbara C van MunsterSophia E J A de Rooij
Aug 19, 2008·Journal of Psychosomatic Research·David J MeagherJouko V Laurila
Sep 25, 2010·Journal of the American Geriatrics Society·Shinya IshiiDebra Saliba
Dec 2, 2010·Internal Medicine Journal·M M Y Lai, D M Wong Tin Niam
Apr 10, 2010·Perspectives in Psychiatric Care·Faruk UguzGökhan Altunbas
Jan 1, 2014·Journal of Clinical Nursing·Irene ErikssonLisbeth Fagerström
Jan 27, 2015·British Journal of Clinical Pharmacology·E A Davies, M S O'Mahony
Jul 28, 2013·Interactive Cardiovascular and Thoracic Surgery·Nina SmulterKarl Gunnar Engström
Jul 22, 2014·Journal of Internal Medicine·P CermakovaD Religa
Feb 11, 2015·Journal of Clinical Nursing·Jenny Day, Isabel Higgins
Oct 18, 2012·Annals of Medicine·Timo E StrandbergTimo J Erkinjuntti
Jul 15, 2015·Journal of the American Medical Directors Association·Kaisu H PitkalaJ Simon Bell
Sep 11, 2012·Cancer Treatment Reviews·Jung Hun KangEduardo Bruera
Jan 2, 2013·International Journal of Surgery·N A O'ReganD Meagher
Jul 10, 2016·Clinics in Geriatric Medicine·Lindsay E Nicolle
Jul 24, 2010·Health and Quality of Life Outcomes·Irene ErikssonBirgitta Olofsson
May 15, 2016·International Journal of Clinical Pharmacy·Hugo A J M de WitJos M G A Schols
Mar 9, 2017·International Journal of Geriatric Psychiatry·Rowan H Harwood, Elizabeth Teale
Feb 12, 2017·European Journal of Anaesthesiology·César AldecoaClaudia D Spies
Sep 3, 2017·Drugs·Shirley Harvey BushPeter Gerard Lawlor
Nov 15, 2019·Palliative & Supportive Care·Annina SeilerSoenke Boettger
Jul 20, 2019·Journal of Alzheimer's Disease : JAD·Pilar Pérez-RosFrancisco Tarazona-Santabalbina
Jul 8, 2020·Nursing in Critical Care·Francesco GravanteRoberto Latina

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

Journal of the American Geriatrics Society
Edward R MarcantonioN M Resnick
The British Journal of Psychiatry : the Journal of Mental Science
David MeagherPaula Trzepacz
The American Journal of Medicine
Linda M Dairiki Shortliffe, Jack D McCue
Journal of Geriatric Psychiatry and Neurology
J ManepalliC Mueller
© 2022 Meta ULC. All rights reserved