PMID: 40306Jan 1, 1979

Prednisone effect on microvascular permeability in patients with inflammatory rheumatic diseases

Scandinavian Journal of Rheumatology
R ManthorpeH E Utne


The transcapillary escape rate of albumin was measured in 27 consecutive patients with inflammatory rheumatic diseases before and after 1 and 7 days of prednisone treatment in doses of 45 mg/day. The transcapillary escape rate decreased from 7.33%/h (range 5.11-9.55) before prednisone treatment to 3.11%/h (0.04-6.18) (p less than 0.05) after 1 day of treatment and 5.80%/h (4.36-7.24) after 7 days of treatment. It is concluded that prednisone inhibits vascular permeability in patients with inflammatory rheumatic diseases.


Mar 25, 1972·British Medical Journal·J MarksS Shuster
May 1, 1973·Circulation Research·H H Parving, F Gyntelberg
Aug 1, 1974·The American Journal of Physiology·H H ParvingN A Lassen
Jun 5, 1971·British Medical Journal·M I Jayson, J S Barks

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