Predominance of a single genotype of Mycobacterium tuberculosis in countries of east Asia.

Journal of Clinical Microbiology
D van SoolingenJ D van Embden

Abstract

Analysis of the population structure of Mycobacterium tuberculosis strains from the People's Republic of China showed that the vast majority belong to a genetically closely related group. These strains shared the majority of their IS6110 DNA-containing restriction fragments, and also, the DNA polymorphism associated with other repetitive DNA elements, like the polymorphic GC-rich sequence and the direct repeat, was very limited. Because the majority of these strains originated from the province of Beijing, we designated this grouping the "Beijing family" of M. tuberculosis strains. Strains of this family were also found to dominate in neighboring countries such as Mongolia, South Korea, and Thailand, whereas a low prevalence of such strains was observed in countries on other continents. These data indicate that strains of the Beijing family recently expanded from a single ancestor which had a selective advantage. It is speculated that long-term Mycobacterium bovis BCG vaccination may be one of the selective forces implicated in the successful spread of the Beijing genotype.

References

Sep 9, 1992·JAMA : the Journal of the American Medical Association·C Beck-SaguéW R Jarvis
May 1, 1994·Journal of Clinical Microbiology·I J WiidP D van Helden

❮ Previous
Next ❯

Citations

Dec 19, 2001·Emerging Infectious Diseases·G E PfyfferJ D van Embden
Jul 27, 2002·Emerging Infectious Diseases·Judith R GlynnDick van Soolingen
Apr 16, 2003·Journal of Applied Microbiology·E KandumaS H Gillespie
Jun 13, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Deepak AlmeidaAjita Mehta
Sep 18, 2003·International Journal of Systematic and Evolutionary Microbiology·Debby V CousinsAmelia Bernardelli
Sep 19, 2003·The New England Journal of Medicine·Peter F Barnes, M Donald Cave
Dec 6, 2003·Proceedings of the National Academy of Sciences of the United States of America·Noel H SmithJohn Maynard Smith
Jan 15, 2004·Emerging Infectious Diseases·Nguyen Thi Ngoc LanDick van Soolingen
Oct 13, 2004·FEMS Immunology and Medical Microbiology·Olga S ToungoussovaGunnar Bjune
Sep 15, 2004·Respirology : Official Journal of the Asian Pacific Society of Respirology·Linh N NguyenGuy B Marks
Jun 23, 2004·Emerging Infectious Diseases·Urvashi Balbir SinghPradeep Seth
Oct 23, 2004·Emerging Infectious Diseases·Lucy BakerFrancis Drobniewski
Mar 1, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Deepak AlmeidaAjita Mehta
May 18, 2006·Emerging Infectious Diseases·Angkana ChaiprasertChertsak Dhiraputra
Oct 17, 2006·Clinical Microbiology Reviews·Barun MathemaBarry N Kreiswirth
Oct 25, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·I MokrousovA D Shen
Sep 18, 2008·Memórias do Instituto Oswaldo Cruz·Viviana RitaccoLucía Barrera
Mar 4, 2011·Future Microbiology·Midori Kato-MaedaLaura Flores
Nov 11, 2011·Journal of Bacteriology·Tohru Miyoshi-AkiyamaTeruo Kirikae
Dec 24, 2013·Scandinavian Journal of Infectious Diseases·Wei LuLimei Zhu
Mar 1, 2014·International Journal of Mycobacteriology·Rashid Ramazanzadeh, Kourosh Sayhemiri
Oct 16, 2016·Current Microbiology·Fatemeh Riyahi ZanianiBahram Nasr Esfahani
Dec 13, 2016·Jundishapur Journal of Microbiology·Leyla SahebiMajid Khalili
Jan 1, 2016·Ci Ji Yi Xue Za Zhi = Tzu-chi Medical Journal·Tao Qian TangChih-Bin Lin
Jan 7, 2020·Pathogens and Global Health·M I Cerezo-CortésM I Murcia

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Microbiology
A KrüünerG Källenius
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
S TheusM D Cave
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
D BalazsM Damian
© 2021 Meta ULC. All rights reserved