PMID: 15220683Jun 29, 2004Paper

Predominant symptom behavior in patients with persistent dyspepsia during treatment

Journal of Clinical Gastroenterology
R J F LaheijJ B M J Jansen

Abstract

Grouping of patients based on a predominant dyspeptic symptom is frequently employed in management strategies for dyspepsia. Such subdivision, however, suggests that dyspeptic symptom patterns are constant over time. To investigate the behavior of symptoms over time and to study the effects of diagnostic procedures and treatment on the pattern and severity of dyspeptic symptoms. Patients with persistent dyspeptic symptoms completed a validated questionnaire at regular time intervals as part of a clinical trial in primary care. Based on predominant symptoms, patients were classified into ulcer-like dyspepsia, reflux-like dyspepsia, dysmotility-like dyspepsia, and unspecific dyspepsia according to the Rome II criteria. Questionnaires were returned at baseline, 1, 3, and 6 months by 185, 172, 169, and 170 patients, respectively. At baseline, 35% of patients reported predominantly reflux-like dyspepsia, 34% had ulcer-like dyspepsia, 16% had dysmotility-like dyspepsia, and in 15% symptoms were not specific. During the 6-month follow-up period, only 35% of patients kept the same predominant symptom. Symptom (in)stability was not dependent on diagnostic procedures or on therapy with proton pump inhibitors, H2-receptor antagonists, pro...Continue Reading

References

Feb 6, 1998·Journal of Clinical Gastroenterology·R J LaheijA L Verbeek
Sep 17, 1998·Journal of Clinical Microbiology·R J LaheijA L Verbeek
Aug 24, 1999·Gut·N J TalleyG N Tytgat

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Citations

Mar 18, 2008·Journal of Clinical Gastroenterology·Steven P HarrellJohn M Wo
Apr 2, 2011·Journal of Gastroenterology and Hepatology·Noriaki Manabe, Ken Haruma
Dec 6, 2012·Gastroenterology Research and Practice·Sylvester Chuks NwokediukoOlive Obienu
Apr 18, 2012·World Journal of Gastroenterology : WJG·Masahiro SakaguchiFumiyuki Takao
May 7, 2008·Journal of Gastroenterology·Brecht Geeraerts, Jan Tack
Apr 1, 2006·Alimentary Pharmacology & Therapeutics·N J TalleyD L Earnest
Mar 31, 2011·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·L Van OudenhoveJ Tack
May 9, 2006·Gastroenterology·Jan TackVincenzo Stanghellini
Aug 10, 2007·Orvosi hetilap·György Miklós Buzás
Jun 18, 2009·The American Journal of Gastroenterology·Yao-Chun HsuMing-Shiang Wu
Feb 13, 2013·Nature Reviews. Gastroenterology & Hepatology·Jan Tack, Nicholas J Talley
Sep 26, 2014·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Jong Kyu ParkUNKNOWN Korean Society of Neurogastroenterology and Motility
May 9, 2008·Digestive Diseases·Nicholas J TalleyHye Kyung Jung
Aug 23, 2008·Journal of Clinical Gastroenterology·Lieke A S van KerkhovenJan B M J Jansen
Aug 19, 2015·Journal of Pediatric Gastroenterology and Nutrition·Rossella TurcoAnnamaria Staiano
Mar 25, 2008·Southern Medical Journal·Navneet AttriA Feller

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