PMID: 9546566Apr 18, 1998Paper

Preemptive epidural analgesia and recovery from radical prostatectomy: a randomized controlled trial

JAMA : the Journal of the American Medical Association
A GottschalkA J Wein

Abstract

Preemptive analgesia can decrease the sensitization of the central nervous system that would ordinarily amplify subsequent nociceptive input, but a clear demonstration of its clinical efficacy is necessary for it to become a routine component of acute pain therapy. To determine the impact of preemptive epidural analgesia on postoperative pain and other clinically important outcome variables after radical retropubic prostatectomy. A block randomized double-blind clinical trial lasting 20 months at a single academic medical center. A total of 100 generally healthy and neurologically intact patients scheduled for radical retropubic prostatectomy for the treatment of prostate cancer in whom an epidural catheter for treating postoperative pain was to be placed prior to the induction of general anesthesia. Epidural bupivacaine, epidural fentanyl, or no epidural drug was administered prior to induction of anesthesia and throughout the entire operation, followed by aggressive postoperative epidural analgesia for all patients. Daily pain scores during hospitalization and pain scores obtained 3.5, 5.5, and 9.5 weeks after hospital discharge. The patients who received epidural fentanyl or bupivacaine prior to surgical incision (preemptive...Continue Reading

Citations

Mar 31, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·D Fletcher, C Jayr
Apr 16, 2013·Naunyn-Schmiedeberg's Archives of Pharmacology·José Christian Machado XimenesGlauce Socorro de Barros Viana
Oct 28, 2003·Annals of Surgery·Robert J MoracaRichard C Thirlby
Jun 29, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Juraj SprungDavid O Warner
Dec 23, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·H ObataF Goto
Jun 27, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Marc A BurmeisterThomas G Standl
Dec 18, 2001·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D J KellyS J Brull
Dec 22, 2010·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Jacques E ChellyJoel B Nelson
Oct 5, 2006·Current Opinion in Anaesthesiology·J Ballantyne
Oct 4, 2006·Current Opinion in Anaesthesiology·J Ballantyne
Oct 3, 2006·Current Opinion in Anaesthesiology·D D Glass
Oct 7, 2006·Current Opinion in Anaesthesiology·Christopher L Wu, Jeffrey M Richman
Oct 6, 2000·Anesthesiology·I Kissin
Oct 3, 2002·Anesthesiology·Michael Andreae
Jan 31, 2002·Anesthesiology·Bertrand Du Manoir, Dominique Fletcher
Sep 10, 2002·Anesthesiology·Christopher L Wu, Srinivasa N Raja
Dec 28, 2002·Anesthesiology·Allan Gottschalk, E Andrew Ochroch
Aug 26, 2006·Anesthesiology·Merlin D LarsonAtsuko Baba
Sep 27, 2008·Pakistan Journal of Biological Sciences : PJBS·Fakharian EsmailTabesh Homayoon
Feb 11, 2000·Journal of the American Veterinary Medical Association·D B SwalanderP J Jahn
Sep 18, 2009·Der Urologe. Ausg. A·A Tahmatzopoulos, O Moormann
May 15, 2001·Anaesthesia·P GillR Atcheson
Dec 22, 2010·British Journal of Anaesthesia·C Voscopoulos, M Lema
May 25, 2002·Orthopaedic Nursing·B Ginsberg
Dec 3, 2013·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·K SenthilV V Ramachandran
Feb 5, 2000·Regional Anesthesia and Pain Medicine·M D Larson, P D Berry
Mar 8, 2002·The Clinical Journal of Pain·Julie HalbertIan D Cameron
May 1, 2009·Expert Review of Neurotherapeutics·Joel Katz, Ze'ev Seltzer
Sep 26, 2007·Expert Review of Anticancer Therapy·Israel P NosnikJudd W Moul
Dec 1, 2009·Journal of Cardiothoracic and Vascular Anesthesia·Erin A Sullivan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Dhruvil R ShahRobert J Canter
Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Wande B PrattCharles M Vollmer
Anesthesia and Analgesia
S Felsby, P Juelsgaard
© 2022 Meta ULC. All rights reserved