Preferences for prenatal diagnosis of sickle-cell disorder: A discrete choice experiment comparing potential service users and health-care providers

Health Expectations : an International Journal of Public Participation in Health Care and Health Policy
Melissa HillLyn S Chitty

Abstract

Non-invasive prenatal diagnosis (NIPD) for sickle-cell disorder (SCD) is moving closer to implementation and studies considering stakeholder preferences are required to underpin strategies for offering NIPD in clinical practice. Determine service user and provider preferences for key attributes of prenatal diagnostic tests for SCD and examine views on NIPD. A questionnaire that includes a discrete choice experiment was used to determine the preferences of service users and providers for prenatal tests that varied across three attributes: accuracy, time of test and risk of miscarriage. Adults who were carriers of SCD or affected with the condition (N=67) were recruited from haemoglobinopathy clinics at two maternity units. Health professionals, predominately midwives, who offer antenatal care (N=62) were recruited from one maternity unit. No miscarriage risk was a key driver of decision making for both service users and providers. Service providers placed greater emphasis on accuracy than service users. Current uptake of invasive tests was 63%, whilst predicted uptake of NIPD was 93.8%. Many service users (55.4%) and providers (52.5%) think pressure to have prenatal testing will increase when NIPD for SCD becomes available. Ther...Continue Reading

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Citations

Jul 30, 2019·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Domino DetermannLine Bjørnskov Pedersen
Feb 26, 2020·British Journal of Haematology·Julia van CampenEugene Oteng-Ntim
Apr 18, 2019·BMC Pregnancy and Childbirth·Caroline M VassKatherine Payne
Feb 6, 2021·Implementation Science : IS·Ann DadichDominiek Coates
Aug 20, 2021·British Journal of Haematology·Eugene Oteng-NtimUNKNOWN British Society for Haematology Guideline

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