Preferential blockade of presynaptic alpha-adrenoceptors by yohimbine

European Journal of Pharmacology
K StarkeT Endo

Abstract

Strips of the rabbit main pulmonary artery were preincubated with 3H-noradrenaline. 3 X 10(-8) -- 10(6) M yohimbine enhanced the overflow of tritium and the smooth muscle contraction induced by transmural sympathetic nerve stimulation. The increase of the stimulation-evoked overflow of tritium was prevented by a high concentration of oxymetazoline. The results indicate that yohimbine is more potent in blocking the presynaptic than the postsynaptic alpha-adrenoceptors of the artery.

Citations

Dec 1, 1993·Naunyn-Schmiedeberg's Archives of Pharmacology·B SzaboK Starke
Jan 1, 1986·Psychopharmacology·M P Parale, S K Kulkarni
Jan 1, 1983·Psychopharmacology·F EdwardsO Jenkins
Jan 1, 1989·Psychopharmacology·F FerrariV Mangiafico
Dec 1, 1982·Naunyn-Schmiedeberg's Archives of Pharmacology·B RouotJ Schwartz
Nov 1, 1980·Naunyn-Schmiedeberg's Archives of Pharmacology·A T Sullivan, G M Drew
Feb 1, 1977·Naunyn-Schmiedeberg's Archives of Pharmacology·T EndoH D Taube
Mar 20, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·P B TimmermansP A van Zwieten
Jan 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·R W Rockhold, F Gross
Feb 1, 1982·Naunyn-Schmiedeberg's Archives of Pharmacology·P T HornL I Goldberg
Apr 1, 1983·Naunyn-Schmiedeberg's Archives of Pharmacology·G H Paalzow, L K Paalzow
Jan 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·A R Wakade, T D Wakade
Jul 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·H C InnemeeP A van Zwieten
Sep 1, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·H J Schümann, O E Brodde
Dec 1, 1983·Naunyn-Schmiedeberg's Archives of Pharmacology·T ShojiT Shigei
Dec 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·N B Shepperson, S Z Langer
Nov 1, 1980·Naunyn-Schmiedeberg's Archives of Pharmacology·J W Constantine, W Lebel
Nov 1, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·T Tanaka, K Starke
Aug 1, 1984·Naunyn-Schmiedeberg's Archives of Pharmacology·S L Handley, S Mithani
Aug 1, 1980·Naunyn-Schmiedeberg's Archives of Pharmacology·P B Timmermans, P A van Zwieten
Jul 20, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·R RaismanS Z Langer
Aug 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·N B SheppersonS Z Langer
Aug 1, 1982·Naunyn-Schmiedeberg's Archives of Pharmacology·T NakadateR Kato
May 28, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·M C Koss, H D Christensen
Dec 1, 1984·Naunyn-Schmiedeberg's Archives of Pharmacology·B CostallC C Tan
Jan 1, 1981·European Journal of Clinical Pharmacology·B I Nesheim, T Saetre
Dec 1, 1986·Naunyn-Schmiedeberg's Archives of Pharmacology·R P McAdams, J F Waterfall
Oct 1, 1982·Naunyn-Schmiedeberg's Archives of Pharmacology·R A Hahn, B R MacDonald
Oct 1, 1982·Naunyn-Schmiedeberg's Archives of Pharmacology·A R Wakade, T D Wakade
Jan 1, 1986·Psychopharmacology·M P Parale, S K Kulkarni
Oct 1, 1986·Biulleten' eksperimental'noĭ biologii i meditsiny·B V Andreev, Iu D Ignatov
Jan 1, 1980·Neir̆ofiziologiia = Neurophysiology·I V Komissarov, I I Abramets
Jan 1, 1988·Journal of Neural Transmission·T AzumaH Yoshida
Jan 18, 2012·Psychopharmacology·Amanda T CampbellFrancesco Leri
Oct 1, 1977·European Journal of Pharmacology·P B Timmermans, P A van Zwieten
Sep 1, 1978·European Journal of Pharmacology·J C DoxeyG Metcalf
May 1, 1978·European Journal of Pharmacology·G A LambertS Gershon
Jul 1, 1978·European Journal of Pharmacology·J W ConstantineW K McShane
Apr 1, 1979·European Journal of Pharmacology·P B TimmermansP A van Zwieten
Sep 1, 1979·European Journal of Pharmacology·J LeightonL L Parmeter
Mar 21, 1980·European Journal of Pharmacology·M F El-Refai, J H Exton
Sep 5, 1980·European Journal of Pharmacology·J W ConstantineR A Weeks
Dec 5, 1980·European Journal of Pharmacology·R Reichl, A Walland
Mar 5, 1981·European Journal of Pharmacology·M GöthertG Weinheimer
Nov 5, 1981·European Journal of Pharmacology·R G PendletonJ P Hieble
Jan 5, 1981·European Journal of Pharmacology·P E McCleary, J D Leander
Jul 16, 1982·European Journal of Pharmacology·S R Carr, J R Fozard
Apr 8, 1982·European Journal of Pharmacology·J W ConstantineR A Weeks
Jun 3, 1983·European Journal of Pharmacology·L P DwoskinS B Sparber
Oct 28, 1983·European Journal of Pharmacology·M AndréjakH Schmitt
Apr 13, 1984·European Journal of Pharmacology·H Ruskoaho, H Karppanen
Feb 26, 1985·European Journal of Pharmacology·A G Ramage, A Tomlinson
Jun 4, 1987·European Journal of Pharmacology·M OhnoS Ueki
Jul 9, 1987·European Journal of Pharmacology·M Fujioka, D W Cheung
Jun 20, 1989·European Journal of Pharmacology·R K MinkesP J Kadowitz
Jan 1, 1980·The International Journal of Biochemistry·E D SaggersonC A Carpenter
Mar 1, 1979·Neuropharmacology·M C Koss, P J Bernthal
Apr 1, 1982·Neuropharmacology·D J JonesS J Enna
Feb 1, 1982·Neuropharmacology·D J JonesS J Enna
Jul 1, 1984·Pharmacology, Biochemistry, and Behavior·P A Caza
Apr 1, 1984·Pharmacology, Biochemistry, and Behavior·M F CallahanG A Oltmans
Feb 1, 1987·Pharmacology, Biochemistry, and Behavior·R D MyersA H Rezvani
Feb 1, 1987·Pharmacology, Biochemistry, and Behavior·M Verleye, F Bernet
May 1, 1987·Pharmacology, Biochemistry, and Behavior·T L Davidson, I Lucki
Apr 1, 1987·Pharmacology, Biochemistry, and Behavior·J L CadetW J Freed
Jan 1, 1988·Pharmacology, Biochemistry, and Behavior·K L Kepler, R J Bodnar
Jan 1, 1989·Progress in Neurobiology·T L Török
Oct 1, 1976·General Pharmacology·K Starke, T Endo
Jan 1, 1981·General Pharmacology·S PatelS C Verma
Jul 1, 1979·Psychoneuroendocrinology·K D CairncrossA F Wren
Feb 1, 1989·Brain Research Bulletin·L M GroverS B Auerbach
Jan 1, 1980·Progress in Neuro-psychopharmacology·H FrancesP Simon
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·T B Ng
Jan 1, 1986·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·T KitazawaH Kondo
Oct 1, 1992·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·Y Iwabuchi, T Masuhara
Mar 1, 1993·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·G Amabeoku, O Chikuni
Apr 1, 1994·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·G AmabeokuE Bwakura
Jan 1, 1982·Progress in Neuro-psychopharmacology & Biological Psychiatry·L Proulx-FerlandJ Cote
Aug 10, 2000·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·G SzabóS Hagl
Mar 11, 2006·International Journal of Impotence Research·G SoydanM Tuncer
Jan 1, 1982·Clinical and Experimental Pharmacology & Physiology·G A McPherson, R J Summers
Jan 1, 1990·Fundamental & Clinical Pharmacology·J F TesteP Rinjard
Dec 1, 1977·British Journal of Pharmacology·J C Doxey, J Everitt
May 1, 1977·British Journal of Pharmacology·J C DoxeyJ M Walker
Jan 1, 1978·British Journal of Pharmacology·I MarshallN B Shepperson
Mar 1, 1979·British Journal of Pharmacology·D A Brown, M P Caulfield
May 1, 1991·British Journal of Pharmacology·N LimbergerK Starke
Feb 1, 1982·Acta Physiologica Scandinavica·M Beausang-Linder
Jan 1, 1990·Annals of the New York Academy of Sciences·T C Westfall
Jul 23, 1999·Annals of the New York Academy of Sciences·M GöthertG J Molderings
Feb 29, 1992·BMJ : British Medical Journal·S Varkey
Feb 1, 1980·Journal of Pharmacological Methods·I L Natoff, B B Dodge
Apr 1, 1985·Pharmacological Research Communications·M CastelliW Ferrari
Sep 1, 1983·Metabolism: Clinical and Experimental·E Zacny, J Bugajski
Jan 1, 1980·Clinical and Experimental Hypertension : CHE·E J Sybertz, B G Zimmerman
Feb 1, 1980·Clinical and Experimental Hypertension : CHE·C GomesB Persson
May 1, 1997·The American Journal of Drug and Alcohol Abuse·F A HameediT R Kosten
Jan 1, 1984·Annals of the New York Academy of Sciences·M L Dubocovich
Jan 1, 1986·Annals of the New York Academy of Sciences·W T Chance
Jun 1, 1984·General and Comparative Endocrinology·F C BuonomoC G Scanes
Jun 10, 1978·Lancet·L M Drummond, A M Veale
Apr 1, 1984·Circulation Research·K JieP A van Zwieten
Jul 1, 1984·Circulation Research·W F Goldman, W R Saum
Sep 1, 1985·Stroke; a Journal of Cerebral Circulation·K Ulrich, W Kuschinsky
Apr 1, 1988·Medicinal Research Reviews·Y BanN Takano
May 1, 1993·Medicinal Research Reviews·R M Pinder, J H Wieringa
Feb 29, 1992·BMJ : British Medical Journal·J C DearloveJ A Henry
Mar 1, 1981·Journal of Autonomic Pharmacology·H E ConnorP E Hicks
Dec 1, 1979·The Journal of Pharmacy and Pharmacology·A Gibson, M Samini
Mar 1, 1981·Journal of Autonomic Pharmacology·P B Timmermans, P A van Zwieten
Oct 1, 1983·The Journal of Pharmacy and Pharmacology·D R Mottram
Apr 1, 1984·The Journal of Urology·W D SteersG S Benson
Mar 1, 1977·British Journal of Pharmacology·K G GreinerJ R Wood
Jan 1, 1990·Journal of Receptor Research·H F MirandaD Bustamante
Jan 1, 1987·Fundamental & Clinical Pharmacology·M SchmidtJ L Imbs
Nov 1, 1980·British Journal of Pharmacology·S O Fagbemi, L A Salako
Jun 1, 1980·The Journal of Pharmacy and Pharmacology·J Brown, S L Handley
Sep 1, 1983·Journal of Autonomic Pharmacology·R K GoyalS C Verma
Feb 1, 1983·British Journal of Pharmacology·N FerryT Sevenet
Mar 1, 1985·The Journal of Pharmacy and Pharmacology·J J PolóniaS Guimarães
Feb 1, 1981·Naunyn-Schmiedeberg's Archives of Pharmacology·G GrossH J Schümann
Aug 1, 1978·The Journal of Pharmacy and Pharmacology·K F Rhodes, J F Waterfall
Jul 1, 1983·Naunyn-Schmiedeberg's Archives of Pharmacology·S GurtuK P Bhargava
Jul 1, 1980·British Journal of Pharmacology·N A Flavahan, J C McGrath
Jul 1, 1982·The Journal of Urology·A MoralesJ Fenemore
Jul 1, 1982·The Journal of Pharmacy and Pharmacology·B Cox, C Ennis
Jun 1, 1978·British Journal of Pharmacology·A Gibson, M Samini
Mar 1, 1983·British Journal of Pharmacology·J C DoxeyC F Smith
May 1, 1984·Naunyn-Schmiedeberg's Archives of Pharmacology·N DeckerJ Schwartz
Apr 26, 1977·Naunyn-Schmiedeberg's Archives of Pharmacology·I Zebrowska-LupinaZ Kleinrok
Jan 1, 1982·Acta Medica Scandinavica. Supplementum·J E Wikberg
Jul 1, 1994·The Journal of the American Paraplegia Society·P W Nance

Related Concepts

Metazoa
Dose-Response Relationship, Drug
Electric Stimulation Technique
Inotropism
Smooth Muscle
Oxymetazoline hydrochloride
Chinchilla Rabbits
Norepinephrine Receptors
Alpha-adrenergic receptor
Sympathetic Nervous System

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.