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Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

Acta Neuropathologica Communications

Oct 22, 2019

Li-Chun LinWilliam W. Seeley

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Abstract

Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterior cingulate cortices (ACC) is observed in patients with sporadic behavioral va...read more

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Acetylation
Cerebral Cortex
Genes
Insula of Reil
Macrophage
Nerve Degeneration
Neurons
Tau Proteins
Pick Disease of the Brain
3'-N-acetylfusarochromanone
9
1
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Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants

Acta Neuropathologica Communications

Oct 22, 2019

Li-Chun LinWilliam W. Seeley

PMID: 31640778

DOI: 10.1186/s40478-019-0809-0

Abstract

Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterior cingulate cortices (ACC) is observed in patients with sporadic behavioral va...read more

Mentioned in this Paper

Acetylation
Cerebral Cortex
Genes
Insula of Reil
Macrophage
9
1

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