PMID: 4636786Apr 1, 1972

Preferential utilization of the glucosyl moiety of sucrose by a cariogenic strain of Streptococcus mutans

Infection and Immunity
C F SchachteleD J Knudson


The utilization of sucrose by a cariogenic strain of Streptococcus mutans was studied. The soluble and cell-bound sucrose-dependent, polymer-forming sucrase activities constitutively produced by the bacteria during growth on glucose were measured. About eight times more dextransucrase activity was present than levan-sucrase activity. During various states of growth on sucrose, S. mutans accumulated two to five times more insoluble and water-soluble dextran than levan. Although more of the fructosyl moiety of sucrose was therefore available to the cells, the glucosyl portion of the disaccharide was preferentially incorporated into cellular macromolecules. Glucose was shown to inhibit the utilization of fructose by S. mutans.


May 1, 1976·Journal of Dental Research·R A CowmanR J Fitzgerald
Nov 1, 1974·Journal of Dental Research·G R GermaineA M Chludzinski
May 1, 1975·Journal of Dental Research·D F Schachtele, W L Leung
Jan 1, 1977·Journal of Dental Research·D W Ellis, C H Miller
Nov 1, 1973·Journal of Dental Research·C F Schachtele, J A Mayo

Related Concepts

Bacterial Proteins
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