Prefrontal brain stimulation during food-related inhibition training: effects on food craving, food consumption and inhibitory control

Royal Society Open Science
Jemma SedgmondRachel C Adams

Abstract

Modulation of dorsolateral prefrontal cortex (DLPFC) activity using non-invasive brain stimulation has been shown to reduce food craving as well as food consumption. Using a preregistered design, we examined whether bilateral transcranial direct current stimulation (tDCS) of the DLPFC could reduce food craving and consumption in healthy participants when administered alongside the cognitive target of inhibitory control training. Participants (N = 172) received either active or sham tDCS (2 mA; anode F4, cathode F3) while completing a food-related Go/No-Go task. State food craving, ad-lib food consumption and response inhibition were evaluated. Compared with sham stimulation, we found no evidence for an effect of active tDCS on any of these outcome measures in a predominantly female sample. Our findings raise doubts about the effectiveness of single-session tDCS on food craving and consumption. Consideration of individual differences, improvements in tDCS protocols and multi-session testing are discussed.

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Citations

Nov 20, 2019·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Carlos Amo UsanosMiguel Alonso-Alonso
Sep 7, 2019·Nutrients·Rachel C AdamsNatalia S Lawrence
Sep 11, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jennifer WagnerElena Rusconi
Nov 18, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Jordan D BeaumontMartin J Barwood
Dec 5, 2021·Reviews in Endocrine & Metabolic Disorders·Theresa Ester, Stephanie Kullmann

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