Prefrontal Cortex Activity Predicts Mental Fatigue in Young and Elderly Men During a 2 h "Go/NoGo" Task

Frontiers in Neuroscience
Asta TerentjevienėAlbertas Skurvydas

Abstract

Background: Although the effects of mental fatigue on cognitive-motor function and psychological state in young adults are well-documented, its effects in the elderly are not completely understood. The aim of this study was to estimate the effect of prolonged cognitive load on the indicators of psychological, cognitive, and motor functions. Methods: Fifteen young and 15 elderly men were asked to perform a 2 h "Go/NoGo" task. Psychological state (mood and motivation), cognitive (prefrontal cortex activity and cognitive performance), and motor (motor cortex excitability and grip strength) functions were measured before and after the task. During the 2 h task, both groups had a significantly similar increase in the number of "Incorrect NoGo" errors. Only in young men reaction time (RT) of "Incorrect NoGo" and intraindividual variability of RT of "Incorrect NoGo" significantly increased during task. After the task, handgrip strength decreased for the young men, whereas latency of motor evoked potentials prolonged both groups. Nevertheless, both groups indicated that they felt fatigue after the 2 h task; we observed that mental demand increased, whereas intrinsic motivation and mood decreased only in young men. Prolonged task decrea...Continue Reading

References

Oct 31, 2000·Journal of the Neurological Sciences·A Chaudhuri, P O Behan
Jun 6, 2002·The Quarterly Journal of Experimental Psychology. A, Human Experimental Psychology·Gerald Matthews, Paula A Desmond
Nov 5, 2002·NeuroImage·Roberto CabezaAnthony R McIntosh
Apr 8, 2003·Acta Psychologica·Dimitri van der LindenTheo F Meijman
Nov 18, 2005·Biological Psychology·Maarten A S BoksemMonicque M Lorist
Feb 6, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Dennis L ReevesRobert L Kane
Jan 4, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sofie HeuninckxStephan P Swinnen
Aug 9, 2008·Brain Research·Monicque M Lorist
Sep 30, 2008·Neuroscience and Biobehavioral Reviews·Frederick Verbruggen, Gordon D Logan
Nov 28, 2008·Annual Review of Psychology·Denise C Park, Patricia Reuter-Lorenz
Oct 24, 2009·Neuroscience and Biobehavioral Reviews·Rachael D SeidlerDavid B Lipps
Mar 24, 2010·Current Opinion in Psychiatry·Junichi Chikazoe
Nov 3, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Albertas SkurvydasVytautas Streckis
Oct 2, 2012·Annual Review of Psychology·Adele Diamond
Jan 21, 2014·Trends in Cognitive Sciences·Michael InzlichtC Neil Macrae
May 23, 2014·Consciousness and Cognition·Carson CookGene A Brewer
Jun 13, 2014·Cognitive, Affective & Behavioral Neuroscience·Todd S BraverUNKNOWN MOMCAI group
Jun 14, 2014·Reviews in the Neurosciences·Akira IshiiYasuyoshi Watanabe
Aug 26, 2014·Neuropsychologia·Roy F Baumeister
Sep 25, 2014·Annual Review of Psychology·Matthew Botvinick, Todd Braver
Oct 1, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Timothy J Buschman, Earl K Miller
Jul 29, 2015·Frontiers in Behavioral Neuroscience·Mónika GergelyfiAlexandre Zénon
Oct 21, 2015·Frontiers in Systems Neuroscience·Matthew R G BrownAndrew J Greenshaw
Mar 8, 2016·Neuropsychologia·Brianne M BettcherJoel H Kramer
Mar 19, 2016·Ageing Research Reviews·Motoaki Sugiura
Oct 25, 2016·Brain and Cognition·Yael NetzAyelet Dunsky
Dec 28, 2016·BioMed Research International·Rima SolianikAlbertas Skurvydas
Apr 11, 2018·Frontiers in Neuroscience·Chun-Hsiang ChuangChin-Teng Lin

❮ Previous
Next ❯

Citations

Jan 23, 2019·Perceptual and Motor Skills·Saulius SukysRasa Kreivyte

❮ Previous
Next ❯

Software Mentioned

fNIRSoft
SSREIT
SPSS Statistics
COBI Studio

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.