PMID: 3768666Sep 10, 1986Paper

Prefrontal unit activity during delayed conditional Go/No-Go discrimination in the monkey. I. Relation to the stimulus

Brain Research
M Watanabe

Abstract

Three monkeys learned a delayed conditional Go/No-go discrimination task. The sequential events of the task were the instructional color stimulus presentation (S1), the first delay (D1), discriminative pattern stimulus presentation (S2), the second delay (D2), and the response (Go or No-go). Single units in the principal sulcus, arcuate area and the inferior convexity of the prefrontal cortex were studied during this task. Of 512 task-related units recorded, 29% had stimulus-related differential activity. Type I units (n = 46) responded differentially to the two S1 stimuli. Type II units (n = 7) responded differentially to the two S2 patterns. Type III units (n = 65) also responded following the S2 presentation, but their activity depended upon whether Go or No-go responses were being signaled, rather than the particular S2 pattern. Type IV units (n = 54) appeared to code both the stimulus properties and behavioral significance of S2. A few premotor units (Area 6) were also examined; they showed either type III (n = 12) or type IV (n = 2) activity. In summary, these results indicate that primate prefrontal cortex participates in visual information processing and may code several aspects of visual stimuli including behavioral si...Continue Reading

References

Jan 1, 1979·Neuropsychologia·C G GrossG L Gerstein
May 1, 1979·Neuroscience Letters·I N PigarevC Scandolara
Jul 15, 1977·Brain Research·E T RollsM K Sanghera
Jul 23, 1976·Brain Research·E T RollsF Mora
Dec 3, 1976·Brain Research·D A Chavis, D N Pandya
Jan 1, 1968·Electroencephalography and Clinical Neurophysiology·E V Evarts
Mar 1, 1969·Brain Research·D N Pandya, H G Kuypers
Oct 26, 1973·Brain Research·C W MohlerR H Wurtz
Jan 1, 1970·Brain : a Journal of Neurology·E G Jones, T P Powell
Jan 1, 1983·Experimental Brain Research·S J ThorpeS Maddison
Mar 30, 1981·Brain Research·C E RosenkildeJ M Fuster
Nov 4, 1960·Science·M L WolbarshtH G Wagner

❮ Previous
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Citations

May 1, 1996·Behavioural Brain Research·K Nakamura, K Kubota
Nov 1, 1994·Neuroscience Research·S Funahashi, K Kubota
Sep 25, 1999·Neuroscience Research·M Sakagami, K Tsutsui
Oct 22, 2003·NeuroImage·Scott A Langenecker, Kristy A Nielson
Jun 14, 2003·Neuropsychology·Martina RiegerKatja Burmeister
Jul 21, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Amy F T Arnsten
Aug 12, 2008·Proceedings of the National Academy of Sciences of the United States of America·Natasha SigalaJohn Duncan
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Meghan L MeyerMatthew D Lieberman
Nov 21, 2007·Cerebral Cortex·Masataka Watanabe, Masamichi Sakagami
Feb 6, 2009·Cerebral Cortex·Makoto KusunokiJohn Duncan
Apr 30, 2009·Annual Review of Neuroscience·Lizabeth M Romanski, Bruno B Averbeck
Jan 1, 1997·Journal of Cognitive Neuroscience·R T Knight
Mar 24, 2009·Journal of Cognitive Neuroscience·Makoto KusunokiJohn Duncan
Oct 23, 2008·BMC Neuroscience·Diane SwickAnd U Turken
Nov 6, 2004·Reviews in the Neurosciences·Yoshikazu Isomura, Masahiko Takada
May 7, 2005·The Spanish Journal of Psychology·Galina I Shulgina
Mar 4, 2009·Cerebral Cortex·Matthew B SprakerDavid E Vaillancourt
Dec 24, 2015·Frontiers in Systems Neuroscience·Farshad A MansouriNafiseh Atapour
Nov 4, 2015·Neuron·Narcisse P BichotRobert Desimone
Nov 5, 2004·The European Journal of Neuroscience·Aureliu LavricSimon Forstmeier
Apr 10, 2007·Annals of the New York Academy of Sciences·Masamichi Sakagami, Masataka Watanabe
Sep 6, 2006·Neural Networks : the Official Journal of the International Neural Network Society·Masamichi SakagamiBob Uttl
Jun 14, 2005·Biological Psychiatry·Amy F T Arnsten, Bao-Ming Li
Apr 11, 2012·The European Journal of Neuroscience·Xiaochuan Pan, Masamichi Sakagami
Oct 14, 2014·The European Journal of Neuroscience·Mikiko KadohisaJohn Duncan
Apr 24, 2012·Progress in Neurobiology·Shintaro Funahashi
Apr 9, 2013·Neuron·Mark G StokesJohn Duncan
Jan 1, 1989·IEEE Transactions on Bio-medical Engineering·E VaadiaM Abeles
Jan 14, 1999·Reviews in the Neurosciences·M Watanabe
Feb 3, 2006·Cerebral Cortex·Anders LedbergRichard Nakamura
Nov 21, 2001·Nature Reviews. Neuroscience·J Duncan
May 14, 2005·Experimental Brain Research·Tamami Fukushi, Toshiyuki Sawaguchi
Jun 18, 2002·Nature Neuroscience·Stefan EverlingJohn Duncan
Oct 7, 2005·Journal of Neurophysiology·Masato Inoue, Akichika Mikami

❮ Previous
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