Pregnancy and bovine somatotropin in nonlactating dairy cows: I. Ovarian, conceptus, and insulin-like growth factor system responses

Journal of Dairy Science
T R BilbyW W Thatcher

Abstract

Nonlactating dairy cows were used to examine effects of bovine somatotropin (bST) on components of the insulin-like growth factor (IGF) system. Estrus was synchronized in cows with a Presynch + Ovsynch protocol and timed AI (TAI; n = 55) or not TAI (cycling, C; n = 23) on d 0 (time of synchronized ovulation). On d 0 and 11, cows received bST (500 mg) or no bST, and were sacrificed on d 17. Pregnancy rates were less in bST cows (27.2%, 9 of 33) than in controls (63.6%; 14 of 22). In contrast, conceptuses were larger in bST-treated cows (39.2 +/- 4.8 cm) than in controls (20 +/- 4.3 cm). Total interferon-tau in uterine luminal flushings (ULF) was greater in bST-treated cows (7.15 > 2.36 microg). Number of class 2 follicles (6 to 9 mm) was less in bST-C cows on d 7 and 16. On d 17, corpus luteum (CL) weight tended to be greater in bST-treated cows. Concentrations of progesterone were greater after d 10 in C than in pregnant (P) cows. In the ULF, IGF-binding protein-3 was greater in bST-P cows than in pregnant cows. A tendency for an increase in IGF-I hormone concentrations in the ULF was detected on d 17 in bST-treated and cyclic cows. Endometrial mRNA for IGF-I, IGF-II, IGFBP-2, and IGFBP-3 increased in bST-C, but not in bST-P co...Continue Reading

References

Apr 1, 1979·Molecular and Cellular Endocrinology·Y KatzD T Armstrong
Sep 1, 1992·Journal of Animal Science·M A McGuireJ J Veenhuizen
May 1, 1991·Journal of Animal Science·L BadingaF W Bazer
Aug 1, 1989·Journal of Animal Science·L M RutterJ G Manns
Oct 22, 1988·BMJ : British Medical Journal·M SagleS Franks
Jan 1, 1981·Methods in Enzymology·P C FamillettiS Pestka
Jul 1, 1983·Analytical Biochemistry·A P Feinberg, B Vogelstein
Jul 1, 1995·Domestic Animal Endocrinology·L J Spicer, S E Echternkamp
Apr 1, 1993·British Journal of Obstetrics and Gynaecology·M TulppalaO Ylikorkala
Dec 1, 1995·DNA and Cell Biology·R BathgateR Ivell
Oct 1, 1996·Biology of Reproduction·R L de la SotaW W Thatcher
Feb 1, 1997·Journal of Dairy Science·J R PursleyM C Wiltbank
Jul 6, 2000·Journal of Dairy Science·F MoreiraW W Thatcher

❮ Previous
Next ❯

Citations

Nov 26, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·M A VelazquezH Niemann
Nov 11, 2005·Journal of the American Veterinary Medical Association·Julian A BartolomeLouis F Archbald
Apr 24, 2013·Reproduction, Fertility, and Development·Lisa M CostelloDermot G Morris
Nov 29, 2013·Biology of Reproduction·Eduardo S RibeiroJosé E P Santos
Nov 19, 2018·Translational Animal Science·Philipe MorielJose L M Vasconcelos

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.