Pregnancy and chronic headache

Expert Opinion on Pharmacotherapy
D A Marcus

Abstract

Headache patterns in women change in relation to fluctuations in oestrogen levels. Increasing oestrogen levels in early pregnancy offer a protective effect against headache, particularly for women with migraine. However, some women continue to experience troublesome headache throughout pregnancy. Headache persisting at the end of the first trimester will usually continue without improvement for the remainder of pregnancy and should be treated. Safe and effective acute care treatment options include paracetamol, opioids and anti-emetics. The use of triptans during pregnancy is controversial and not broadly recommended. Safe and effective preventive treatments include relaxation, biofeedback, beta-blockers, some antidepressants and gabapentin in early pregnancy.

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Citations

Sep 5, 2009·Current Pain and Headache Reports·Sylvia Lucas
Mar 8, 2008·Current Treatment Options in Neurology·Jan Lewis Brandes
Oct 12, 2010·Current Opinion in Obstetrics & Gynecology·Stephen A Contag, Cheryl Bushnell
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Oct 21, 2017·The Journal of Headache and Pain·A NegroUNKNOWN European Headache Federation School of Advanced Studies (EHF-SAS)
Aug 22, 2018·Journal of Women's Health·Rachel A SchroederRebecca A Nebel
Jun 21, 2005·CNS Drugs·Anthony W FoxEgilius L H Spierings
Aug 1, 2019·Arquivos de neuro-psiquiatria·Fernando KowacsMauro Eduardo Jurno

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