PMID: 11344985May 10, 2001Paper

Pregnancy and infection with human immunodeficiency virus

Clinical Obstetrics and Gynecology
L Ahdieh

Abstract

During the past decade, there has been a dramatic increase in the number of women infected with HIV and the number of women with clinical AIDS. One of the most prominent features of HIV infection is that it is usually diagnosed during the peak reproductive years, and in 1998, HIV/AIDS was the fourth leading cause of death among women between the ages of 25 and 44 years. For this reason, there has been long-standing concern regarding the obstetric implications of HIV infection: both the impact of pregnancy on possibly accelerating the course of HIV disease and the impact of HIV infection on the course of pregnancy. There appears to be some immunologic changes associated with pregnancy, but they are not dramatic, and immune markers generally resume their prepregnancy values after delivery. With regard to long-term effects of pregnancy on HIV disease progression, no study to date has shown significant increases in mortality or in AIDS incidence associated with pregnancy. Studies have generally been small, however, and none have accounted for antiretroviral therapy usage. Many studies have shown that certain adverse outcomes are more common in HIV-positive pregnant women as compared with HIV-negative pregnant women, and concerns ha...Continue Reading

References

Jan 1, 1990·American Journal of Obstetrics and Gynecology·H L MinkoffS H Landesman
May 1, 1993·Journal of Acquired Immune Deficiency Syndromes : JAIDS·M M DeschampsW D Johnson
Apr 30, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·M WeisserM Egger
Sep 24, 1998·British Journal of Obstetrics and Gynaecology·R French, P Brocklehurst
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Sep 14, 2000·The New England Journal of Medicine·L M Mofenson

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Citations

May 29, 2003·Journal of Clinical Anesthesia·Krzysztof M Kuczkowski
Aug 24, 2004·International Journal of Obstetric Anesthesia·A M Kruger, S Bhagwanjee
Sep 13, 2014·BMC Health Services Research·Jennifer MoodleyErin Stern
Oct 2, 2007·Journal of Women's Health·Susan AllenAndre Declercq
Apr 28, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·H E OnahT C Oguanuo
Feb 7, 2003·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Anne Katz
Jun 16, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H M SebitloaneTonya M Esterhuizen
Apr 20, 2004·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Sian CottonSusan L Rosenthal
Jan 9, 2004·British Medical Bulletin·James McIntyre
Aug 20, 2004·Journal of Perinatology : Official Journal of the California Perinatal Association·Nikolaos M ZachariasMichael O Gardner

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