Pregnancy and lupus nephritis in developing countries: A systematic review

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Sukriti BansalNilum Rajora

Abstract

Systemic lupus erythematosus (SLE) and lupus nephritis (LN) have a significant impact on the course of pregnancy, as well as on maternal and fetal outcomes. LN in pregnancy can increase the maternal risks of SLE flare, acute kidney injury, preeclampsia, and even death. It also affects fetal outcomes by the increased risk of intrauterine growth retardation, premature delivery, and fetal loss. Successful pregnancy outcomes have been well documented in the developed world, but less is known about patients in developing nations. We searched PubMed and Google scholar for all articles published from 1999 to 2016 in developing countries. Twelve of 13 studies were included excluding only one. All studies were independently reviewed. Most of the studies reported a significant association between high flare rates of LN and higher rates of disease flare. Higher rates of active disease at conception were associated with lower live birth rates. Similarly, high flare rates of LN were associated with higher rates of fetal loss. With regard to geographic trends, Indian studies reported lower overall live birth rates and higher rates of active disease at conception. Interestingly, lower rates of preeclampsia were also noted in Indian studies. H...Continue Reading

References

Apr 1, 1999·The Australian & New Zealand Journal of Obstetrics & Gynaecology·N AggarwalP Bambery
Aug 11, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Todd J StanhopeVesna D Garovic
Aug 28, 2013·Advances in Chronic Kidney Disease·Andrew SmythVesna D Garovic
Nov 19, 2013·Best Practice & Research. Clinical Rheumatology·Aisha Lateef, Michelle Petri
Jan 15, 2014·Current Opinion in Rheumatology·Erica Peart, Megan E B Clowse
Apr 7, 2015·Expert Review of Clinical Immunology·Claudio Ponticelli, Gabriella Moroni
Nov 18, 2015·Seminars in Nephrology·Savino SciasciaDario Roccatello
Nov 18, 2015·Seminars in Nephrology·Andrea G Kattah, Vesna D Garovic
May 5, 2016·European Journal of Internal Medicine·Gabriella Moroni, Claudio Ponticelli
Oct 26, 2016·Journal of Autoimmunity·Gabriella MoroniMarta Mosca
Oct 26, 2016·Journal of Autoimmunity·Maria Grazia LazzaroniAngela Tincani
Aug 19, 2016·Kidney Diseases·Desmond Y H Yap, Tak Mao Chan
Aug 26, 2016·Nature Reviews. Rheumatology·Erin E CarterAnn E Clarke
Sep 17, 2016·Ghana Medical Journal·Ida Dzifa DeyMichael Mate-Kole

❮ Previous
Next ❯

Citations

Jan 13, 2021·Rheumatology International·Vineeta ShobhaRamnath Misra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Journal of the American Society of Nephrology : CJASN
Todd J StanhopeV D Garovic
Best Practice & Research. Clinical Rheumatology
M Khamashta
Terapevticheskiĭ arkhiv
N B GordovskaiaA V Khlopiannikova
© 2021 Meta ULC. All rights reserved