Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome

American Journal of Obstetrics and Gynecology
Shell F WongPeggy Y H Tan

Abstract

This study was undertaken to evaluate the pregnancy and perinatal outcomes of pregnant women with severe acute respiratory syndrome (SARS). All pregnant women (12) who presented with SARS in Hong Kong between February 1 and July 31, 2003, were included. The pregnancy and perinatal outcomes were collected. Evidence of perinatal transmission of virus was assessed with the SARS-associated coronavirus reverse-transcriptase polymerase chain reaction on cord blood, placenta tissue, and subsequent follow-up of the neonate on serology. Three deaths occurred among the 12 patients, giving a case fatality rate of 25%. Four of the 7 patients (57%) who presented in the first trimester had spontaneous miscarriage. Four of the 5 patients who presented after 24 weeks were delivered preterm. Two mothers recovered without delivery, but their ongoing pregnancies were complicated by intrauterine growth restriction. No newborn infant had clinical SARS and all investigations were negative for SARS. SARS during pregnancy is associated with high incidences of spontaneous miscarriage, preterm delivery, and intrauterine growth restriction. There is no evidence of perinatal SARS infection among infants born to these mothers.

References

Feb 1, 1978·Teratology·V H FermL Kilham
Jul 1, 1978·British Journal of Obstetrics and Gynaecology·A B Alaily, K B Carrol
Sep 1, 1989·American Journal of Obstetrics and Gynecology·N E MadingerA G Ellrodt
Jul 28, 1988·The New England Journal of Medicine·A J WilcoxB C Nisula
Jan 1, 1980·Toxicology and Applied Pharmacology·D M KochharT B Knudsen
May 1, 1993·American Journal of Reproductive Immunology : AJRI·D A ClarkB A Croy
Apr 3, 2003·The New England Journal of Medicine·Kenneth W TsangKar N Lai
Apr 16, 2003·The New England Journal of Medicine·Nelson LeeJoseph J Y Sung
Apr 12, 2003·The New England Journal of Medicine·Thomas G KsiazekUNKNOWN SARS Working Group
Apr 25, 2003·Lancet·J S M PeirisUNKNOWN SARS study group
Jan 14, 2004·Emerging Infectious Diseases·Owen Tak-Yin TsangSik-To Lai

❮ Previous
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Citations

Apr 1, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A GagneurC Payan
Sep 6, 2011·Prehospital and Disaster Medicine·Karen P PhillipsCarol A Amaratunga
Jan 16, 2009·Biology of Reproduction·Peyman BizargityElizabeth A Bonney
Oct 11, 2005·Critical Care Medicine·William H Goodnight, David E Soper
Mar 14, 2007·Current Opinion in Obstetrics & Gynecology·Ryan E Longman, Timothy R B Johnson
May 4, 2010·Clinical Obstetrics and Gynecology·Cornelia R Graves
Apr 23, 2008·Current Opinion in Pulmonary Medicine·David S Hui, Paul K S Chan
Oct 16, 2007·Clinical Microbiology Reviews·Vincent C C ChengKwok Yung Yuen
Oct 26, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·A M Li, P C Ng
Feb 8, 2007·Emerging Infectious Diseases·Denise J JamiesonSonja A Rasmussen
Jan 25, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·R T KilaniL J Guilbert
Jan 30, 2014·The Journal of Infectious Diseases·Daniel C PayneUNKNOWN Jordan MERS-CoV Investigation Team
Oct 1, 2005·American Journal of Public Health·Sonja A Rasmussen, Edward B Hayes
Aug 3, 2010·Infectious Disease Clinics of North America·David S C Hui, Paul K S Chan
Feb 23, 2010·Infectious Disease Clinics of North America·Dennis J CleriJohn R Vernaleo
Feb 8, 2005·Pediatric Annals·Paul J Lee, Leonard R Krilov
Sep 25, 2007·Pathologie-biologie·A GagneurC Payan
Apr 3, 2007·International Journal of Obstetric Anesthesia·S Grisaru-GranovskyA Samueloff
Jan 31, 2006·Immunology and Allergy Clinics of North America·Vanessa Laibl, Jeanne Sheffield
Aug 9, 2005·Clinics in Perinatology·Robert L GoldenbergDerek C Johnson
Aug 9, 2005·Clinics in Perinatology·Vanessa R Laibl, Jeanne S Sheffield
Jan 15, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nikolaos E EvangelinakisDemetrios P Kassanos
May 30, 2006·American Journal of Obstetrics and Gynecology·Denise J JamiesonTracee A Treadwell
Oct 29, 2008·Infectious Disease Clinics of North America·Regan N TheilerDenise J Jamieson
Jun 22, 2016·The Journal of Obstetrics and Gynaecology Research·Ji-Ping LiaoCheng-Li Que
Jul 1, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Abdullah AssiriJohn T Watson
Mar 15, 2014·Current Opinion in Pulmonary Medicine·David S HuiAlimuddin Zumla
Mar 5, 2016·BMC Infectious Diseases·Haleema AlserehiBasem Alraddadi
Jul 21, 2017·Emerging Infectious Diseases·Jennifer L LenahanHelen Y Chu
Mar 19, 2020·AJR. American Journal of Roentgenology·Dehan LiuChuansheng Zheng
Mar 13, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shaoshuai WangLing Feng
Mar 21, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Dunjin ChenMichael A Belfort
Apr 1, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Federica CapannaGian Carlo Di Renzo
Mar 3, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Xiaotong WangXinghua Shen
Mar 29, 2020·Journal of Medical Virology·Yu ChenZhi-Ying Yu
Apr 8, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Mehreen Zaigham, Ola Andersson
Apr 6, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Liona C PoonMoshe Hod
Apr 25, 2020·Journal of Medical Virology·Dawei LuXiu-An Yang
Mar 18, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E MullinsE Morris
May 8, 2020·Journal of Psychosomatic Obstetrics and Gynaecology·Elisabetta MicelliMaria Elisabetta Coccia
Apr 14, 2020·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Suliman KhanGuang Han
Apr 16, 2020·Drugs & Therapy Perspectives : for Rational Drug Selection and Use·Sumaira OmerZaheer Ud Din Babar
Mar 5, 2020·BJOG : an International Journal of Obstetrics and Gynaecology·Msq ChuaH K Tan

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Methods Mentioned

BETA
pregnancy tests
cesarean section

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