PMID: 8335137Mar 1, 1993Paper

Pregnancy at forty and over: a case-control study

European Journal of Obstetrics, Gynecology, and Reproductive Biology
P VercelliniA Cardinale

Abstract

We compared obstetric prognosis in 327 women > or = 40 years old (148 nulliparas, 279 multiparas) with 20-30-year-old matched controls who delivered at our department between 1988 and 1990. Gestational diabetes and chronic hypertension were the only more frequent antepartum complications in cases than controls (2.4% vs. 0.3% and 3.4% vs. 0.3%, respectively). There were more premature deliveries in cases than controls (19% vs. 8%) but no difference in postdate deliveries. Cesarean section was more frequent in cases than controls in both nulliparas (64% vs. 30%) and multiparas (43% vs. 12%). Incidence of abdominal delivery for acute obstetrical indications was not increased in older gravidas. Significant differences were observed in low birthweight (17% vs. 5%) and 5-min Apgar score < 7 (8% vs. 2%). Most of the abnormal Apgar scores were recorded after cesarean section; values for vaginally-delivered infants were comparable in older and younger women. Perinatal mortality was similar in the two groups.

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Citations

Dec 20, 2003·Archives of Gynecology and Obstetrics·Hamisu M SalihuGreg R Alexander
Jun 1, 1996·Obstetrics and Gynecology·A BiancoR L Berkowitz
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