PMID: 8612359Sep 1, 1995Paper

Pregnancy complicated by sickle hemoglobinopathy

Clinical Obstetrics and Gynecology
O A Rust, K G Perry

Abstract

During the last decade it has been shown that patients with major sickle hemoglobinopathies can experience a normal reproductive outcome. This has been accomplished with early aggressive prenatal care, effective counseling, and appropriate intervention by providers with a high index of suspicion for factors that lead to untoward outcomes in such women. Because controversy surrounds the use of transfusion therapy for pregnant patients with sickle cell disease, individualization should depend on patient circumstances and provider experience because this is a key factor in the management of these women. New therapies for those with major sickle hemoglobinopathy are on the horizon, but their use in pregnancy awaits further evaluation.

Citations

Jul 31, 1999·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·F M DiejomaohA D Adekile
Nov 24, 2004·Clinical Evidence·Martin Meremikwu
Jun 28, 2000·The Australian & New Zealand Journal of Obstetrics & Gynaecology·P Ladwig, H Murray
Oct 11, 2005·Hematology/oncology Clinics of North America·Kathryn Hassell
Jun 3, 1998·British Journal of Obstetrics and Gynaecology·N van den Broek
Apr 18, 1998·Gastroenterology Clinics of North America·I E Mayer, H Hussain

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