Pregnancy outcome after multifetal pregnancy reduction

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
A AntsaklisS Mesogitis

Abstract

To study the effects of multifetal pregnancy reduction (MFPR) as a means to reduce the adverse outcome of multiple gestations. This was a retrospective study evaluating the outcome of 334 multiple pregnancies after embryo reduction. In 313 multiple pregnancies in which MFPR was performed before 15 weeks, the rates of miscarriage, preterm delivery <33 weeks, preterm delivery <36 weeks and total fetal loss were 9.12%, 13.33%, 38.60% and 16.25%, respectively, and median gestational age at delivery was 35 weeks. There was a significant correlation between miscarriage and the finishing number of fetuses. In 185 triplets reduced to twins, miscarriage, preterm delivery <33 weeks, preterm delivery <36 weeks and total fetal loss occurred in 8.25%, 11.18%, 40.59% and 15.41% of cases, respectively, and median gestational age at delivery was 36 weeks. In the subgroup of 32 reduced triplet pregnancies that also had second-trimester amniocentesis, the risk of miscarriage (3.13%) was not significantly different from that in the rest of the group. Among 21 twin pregnancies that had selective termination at or after 15 weeks, the risk of preterm delivery <33 weeks was three times higher than in the group of 22 twin pregnancies with first-trimes...Continue Reading

References

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Citations

Sep 13, 2006·Journal of Perinatal Medicine·Ola Didrik Saugstad
Dec 9, 2010·Journal of Perinatal Medicine·Aris Antsaklis, Eleftherios Anastasakis
Jan 21, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Joseph HassonJoseph Har-Toov
Jun 15, 2015·American Journal of Obstetrics and Gynecology·Simi GuptaAndrei Rebarber
Jun 22, 2015·Human Reproduction·L van de MheenE Pajkrt
Jul 25, 2020·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Mi Sun KimMin Jung Baek
Aug 14, 2020·Seminars in Immunopathology·Ignacio ValenzuelaLiesbeth Lewi

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