Pregnancy outcome among non-participants in a trial on ultrasound screening

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
H KielerO Axelsson

Abstract

Our objective was to characterize and evaluate pregnancy outcome in women who declined participation in a trial on ultrasound screening in the second trimester. Between 1985 and 1987, 8768 women were recruited for a trial on ultrasound screening. By randomization, 4997 women were assigned to either a screening or a non-screening group. Of the 1414 excluded women, data were retrieved from 1211 (86%). Participation was declined by 526 of these 1211 women, either because of anxiety regarding harmful effects of ultrasound or because they could see no benefits of ultrasound scanning. Non-participants and participants were compared. The non-participants were older, had a higher birth/pregnancy ratio, were less often smokers, and had fewer ultrasound examinations than the participants. There was a longer mean pregnancy length, an increased number of post-term deliveries, more suspicions of small-for-gestational-age fetuses and later detections of multiple pregnancies among non-participants as compared with the screening group. No differences in neonatal morbidity were found except for a greater number of mild respiratory disorders in the non-participant group. The non-participant women were more obstetrically experienced and showed in...Continue Reading

Citations

May 21, 2005·BMJ : British Medical Journal·Gunn Elisabeth VistAndrew David Oxman
Mar 18, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M R TorloniUNKNOWN ISUOG-WHO Fetal Growth Study Group
Nov 10, 2009·Prenatal Diagnosis·Laura E HoustonGeorge A Macones
Sep 2, 2016·Autism Research : Official Journal of the International Society for Autism Research·Sara Jane WebbPierre D Mourad
Feb 15, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·S K NijjarK S Khan
Apr 13, 2005·Epidemiology·Helle KielerOve Axelsson

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