PMID: 9419762Apr 1, 1994Paper

Pregnancy outcome following ultrasound-detected fetal cardiac activity in women with a history of multiple spontaneous abortions

Journal of the Society for Gynecologic Investigation
M R LauferJ A Hill

Abstract

To determine whether women with two or more previous spontaneous abortions of unknown etiology, by conventional testing criteria, have a different rate of subsequent fetal loss than controls after ultrasonic documentation of fetal cardiac activity. Medical records were reviewed from 185 women with spontaneous abortion of unknown etiology. Of these women, 91.9% were found to have evidence of cellular immunity to trophoblast and were treated with progesterone for immunosuppression. Ultrasound evaluation was obtained at 5-6 weeks' gestation to document fetal cardiac activity. A control group of 63 women was also studied. All women were followed for pregnancy outcome. A total of 248 pregnancies were identified from the 185 study patients with multiple spontaneous abortions. Fetal cardiac activity was visualized by ultrasound in 209 pregnancies from 171 study subjects; of these, the outcomes of 208 pregnancies were known. The rate of spontaneous abortion after ultrasound documentation of fetal cardiac activity was 22.7%. Neither maternal age nor number of previous losses was associated with an increased incidence of spontaneous abortion following documentation of fetal cardiac activity. The rate of spontaneous abortion in the contro...Continue Reading

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Citations

Jul 27, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·H J A Carp
Jul 28, 2016·Clinical Obstetrics and Gynecology·Karen J Gibbins, T Flint Porter
Mar 15, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Howard Carp

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