Abstract
To analyze the pregnancy complications and pregnancy outcome relating to the disease activity of systemic lupus erythematosus before conception and during pregnancy. Seventy-two pregnancies were collected in a single tertiary medical center within a 5-year period. Twelve pregnancies were terminated due to various causes in the first half of pregnancy. Analysis of pregnancy complications and pregnancy outcome relating to the lupus activity before conception and during pregnancy was made among the remaining 60 pregnancies with gestational length > 26 weeks. The assessment of lupus activity was based on the routine monitoring, including urine routine, white blood cell count, hemoglobin and platelet count, erythrocyte sediment rate, serum titers of C3, C4, and double-stranded DNA. Monitoring of renal function with daily urinary protein loss and clearance rate of creatinine was needed when worsened nephropathy was suspected. The etiologies of the terminated pregnancies were deteriorated nephropathy (6 cases), involvement of central nervous system (1 case), unwanted pregnancy due to drug exposure (3 cases), and two early intrauterine fetal deaths (both during the 23(rd) week of gestation). Pregnancy complications were related to the ...Continue Reading
References
Dec 1, 1991·Arthritis and Rheumatism·M PetriJ Repke
Sep 1, 1995·Obstetrics and Gynecology·M J JohnsonJ T Repke
Jun 1, 1996·Lupus·M J Davis, A D Woolf
Oct 31, 1998·Lupus·C Gordon, M D Kilby
Sep 15, 2000·Rheumatology·P E GeorgiouA A Drosos
Jul 4, 2001·Lupus·R A LevyN R Jesús
Apr 16, 2002·Arthritis and Rheumatism·Andrea DoriaPier Franca Gambari
Jun 6, 2002·Rheumatology·J Cortés-HernándezM Vilardell-Tarres
Oct 28, 2003·Clinical Rheumatology·M BoyanovP Popivanov
Nov 13, 2003·Arthritis and Rheumatism·Nathalie Costedoat-ChalumeauJean-Charles Piette
May 4, 2004·Best Practice & Research. Clinical Rheumatology·Monika Østensen
Jun 9, 2004·Joint, Bone, Spine : Revue Du Rhumatisme·Olivier Meyer
Feb 5, 2005·Arthritis and Rheumatism·Megan E B ClowseMichelle Petri
Mar 9, 2005·Lupus·Y MoladJ Bar
Oct 6, 2005·American Journal of Obstetrics and Gynecology·J Patricia DharRobert J Sokol
Dec 13, 2005·Lupus·A GuptaR Handa
Apr 8, 2006·Journal of the Chinese Medical Association : JCMA·Ming-Jie YangHsiao-Yi Lin
Jan 27, 2016·Lupus·K Schreiber
Citations
Jun 7, 2016·Clinics in Dermatology·Joy WanVictoria P Werth
Jan 27, 2015·Journal of the Chinese Medical Association : JCMA·Peng-Hui WangFa-Kung Lee
Mar 5, 2016·Journal of the Chinese Medical Association : JCMA·Wen-Ling LeePeng-Hui Wang
May 5, 2016·European Journal of Internal Medicine·Gabriella Moroni, Claudio Ponticelli
Sep 21, 2019·PloS One·Syahrul Sazliyana ShaharirRahana Abdul Rahman
Jul 15, 2020·Lupus·Syahrul S ShaharirRahana A Rahman
Jul 29, 2019·Clinical Rheumatology·Elham RajaeiZeinab Deris Zayeri
Jan 8, 2021·Lupus·Jian ChenJian-Yu Zhang
Aug 5, 2021·Journal of Tropical Pediatrics·Pattima PakhathirathienGunlawadee Maneenil