PMID: 22555133May 5, 2012Paper

Pregnancy outcomes among solid organ transplant recipients in British Columbia

Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC
Robert A HumphreysMina Matsuda-Abedini

Abstract

Since 1954, over 14 000 women have given birth after having had an organ transplantation. Unfortunately, some women and physicians remain misinformed about the feasibility and outcomes of pregnancy post transplantation. Our primary objective was to assess their perceptions and difficulties with regard to becoming pregnant. Our secondary objectives were to determine the incidence of pregnancies among transplant recipients in British Columbia and any maternal, graft, or fetal complications. From 1997 to 2007 in British Columbia, there were over 500 female recipients of solid organ transplants. We surveyed recipients in this group who were of child-bearing age. One hundred forty of 295 (47%) eligible recipients responded: 44 of these women had attempted pregnancy after transplant, and 31 women gave birth to 47 children. One half of the respondents planned to have children post transplant; 108 of 140 (77%) had no children before transplant. One quarter of the respondents were advised against pregnancy by their physician, and 33% of these women found a new physician to support their pregnancy. Rates of miscarriage (27%), rejection (21%), and prematurity (65%) were higher than expected. Infections were rare, and no birth defects or n...Continue Reading

Citations

Mar 27, 2013·British Journal of Clinical Pharmacology·Songmao ZhengMary F Hebert
Oct 2, 2014·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Zoulikha Jabiry-ZieniewiczMiroslaw Wielgos
Feb 12, 2020·BMJ Case Reports·Rubina SohailAsifa Noreen
Dec 4, 2013·Transplantation·Munire Erman Akar
Apr 15, 2018·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Nusrat ZaffarRohan D'Souza
Feb 20, 2019·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Torki Al-OtaibiAhmed F Atta
Feb 29, 2020·Trends in Immunology·Jasper IskeStefan G Tullius

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