Pregnancy outcomes in women complicated by thalassemia syndrome at Maharaj Nakorn Chiang Mai Hospital

Archives of Gynecology and Obstetrics
Kuntharee TraisrisilpTheera Tongsong


To determine the maternal and fetal outcomes of women complicated with thalassemia syndrome. Retrospective descriptive study. The database of Maternal-Fetal Medicine unit and medical records, between January 2001 and April 2008, were reviewed to search for pregnant women complicated with thalassemia syndrome and medical records were reviewed for patient's baseline characteristics and pregnancy outcomes. The inclusion criteria consisted of (1) pregnant women diagnosed for thalassemia syndrome by hematologist either during or before pregnancy based on hemoglobin typing, (2) attending the antenatal care clinic and delivery at Maharaj Nakorn Chiang Mai hospital, and (3) available data of pregnancy outcomes. During the study period, 80 pregnant women with thalassemia syndrome were recruited, including 52 (65%) cases of HbH disease, 23 (28.8%) cases of beta-thalassemia/HbE disease, 2 cases of AE Bart's disease, 2 cases of EF Bart's disease and 1 case of beta-thalassemia major. Excluding 2 twin pregnancies and 1 case with beta-thalassemia major, 77 were available for analysis of the outcomes. The mean gestational age (+/-SD) at delivery was 37.40 (+/-2.6) weeks, range 27-42 weeks. Twenty-five (32.5%) had delivery by cesarean section a...Continue Reading


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Related Concepts

Postcesarean Section
Fetal Growth Retardation
Low Birth Weight Infant
Pregnancy Complications, Hematologic
Thalassemia Minor
Premature Birth
Anemia, Sickle Cell
Beta Thalassemia
Cesarean Section

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