Pregnancy-related obstetric and cardiologic problems in women after atrial switch operation for transposition of the great arteries

Circulation Journal : Official Journal of the Japanese Circulation Society
Vasiliki TrigasHarald Kaemmerer

Abstract

The number of women with congenital heart disease reaching reproductive age has increased due to therapeutic advances. The aim of this study was to examine obstetric and cardiac problems during pregnancy after Mustard/Senning repair for transposition of the great arteries. Sixty pregnancies in 34 women from 3 centers were studied. The women were interviewed, and their records reviewed for clinical status and diagnostic evaluation. Age range was 16-34 years during first pregnancy, and all were in a low functional class. There were 11 miscarriages and 5 abortions. Of 44 successful pregnancies, 20 were vaginal deliveries and 24, cesarean sections. A total of 25% were delivered prematurely. Thirteen babies had birth weight <2,500g. Deterioration in functional class occurred in 7 pregnancies, without recovery in 5. Deterioration in systolic function occurred in 4 of 44 echocardiographically documented pregnancies, without recovery in 75%. In 2 women resuscitation was necessary during delivery, in 1, supraventricular tachycardia occurred during labor. Pregnancy is usually well-tolerated, but outcome is unforeseeable and life-threatening problems can occur. These women belong in cardiac care conducted by experienced congenital cardiol...Continue Reading

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Citations

Jul 4, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·S CataldoS L Curtis
Jun 27, 2015·European Heart Journal·Matthias Greutmann, Petronella G Pieper
Apr 12, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Christopher P Learn, John Lynn Jefferies
Apr 14, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Magdalena LipczyńskaPiotr Hoffman
Jun 24, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Marc-André KoertenUlrike M M Bauer
Jul 23, 2016·Journal of the American College of Cardiology·Uri ElkayamCandice K Silverside
Jan 14, 2017·Circulation·Mary M CanobbioUNKNOWN American Heart Association Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Cardiova
Aug 24, 2017·Cardiology in Review·Despina NtiloudiHaralambos Karvounis
Aug 3, 2021·Frontiers in Pediatrics·Shao-Ju ChienYao-Hsu Yang

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