Pregnancy with concomitant chorangioma and placental vascular malformation with mesenchymal hyperplasia

Human Reproduction
C P ChenC Y Chuang

Abstract

We present two pregnancies associated with normal live births and the unusual concomitance of chorangioma and placental vascular malformation with mesenchymal hyperplasia. The enlarged placenta had the characteristic findings of chorangioma, dilated and varicose chorionic vessels and multiple vesicle-like villi containing hyaluronic acid. The vesicle-like villi showed diploid cellular DNA contents. Molecular genetic analysis using the polymerase chain reaction amplification of polymorphic microsatellite markers confirmed genetic identity among the chorangioma, the vesicle-like villi and the fetus. Both pregnancies were complicated by polyhydramnios, pre-term labour and prematurity. One neonate suffered from anaemia and thrombocytopenia. Another neonate suffered from haemangiomatosis. Our cases demonstrate that concomitant chorangioma and placental mesenchymal hyperplasia are genetically identical to the fetus and can coexist with a normal viable fetus. Since haemangiomas, chorangiomas, chorionic vessels and villi mesenchymal cells are all derived from the mesoderm, a combination of fetal haemangiomas, placental vascular malformation, chorangiomas and placental mesenchymal hyperplasia may represent a mixed form of congenital mal...Continue Reading

Citations

Nov 5, 2008·Archives of Gynecology and Obstetrics·Daphne C AngVinay Prasad
Nov 13, 2001·Obstetrics and Gynecology·Y KuwabaraS Shin
Dec 12, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ingrid WittersJean Pierre Fryns
Sep 30, 2000·Pathology International·M OhyamaY Tanaka
Aug 23, 2002·Pathology·Julie LokanFranca Agnesta
Jul 11, 2013·Case Reports in Obstetrics and Gynecology·Wu QichangXu Yasong
May 20, 2014·Pathology, Research and Practice·Alessia SelminDario Gregori
Mar 18, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Dimitrios PapoutsisAris Antsaklis
Jan 1, 2009·Fetal and Pediatric Pathology·Fabienne AlliasMojgan Devouassoux-Shisheboran
Apr 29, 2014·Taiwanese Journal of Obstetrics & Gynecology·Chih-Ping ChenWayseen Wang
Aug 5, 2008·Annales de pathologie·Fabienne AlliasMojgan Devouassoux-Shisheboran
Jan 10, 2004·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Yuen F Chan, Amanda Sampson
Nov 25, 2003·Pathology International·Hideo MatsuiSouei Sekiya
Jan 11, 2007·The Journal of Obstetrics and Gynaecology Research·Toshihiko KinoshitaMotohiro Itoh
Dec 15, 2012·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·U A NayeriA K Sfakianaki
Jul 17, 2015·The Journal of Obstetrics and Gynaecology Research·Satoshi IshikawaHisanori Minakami
Aug 15, 2015·Indian Journal of Pathology & Microbiology·Krishna G Balachandran NairSantha Sadasivan
Sep 8, 2016·Pediatric Dermatology·Antonia Reimer, Peter H Hoeger
Mar 26, 2005·Prenatal Diagnosis·Marta C CohenDilly O C Anumba
Feb 27, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Edi VaisbuchSonia S Hassan
Mar 14, 2003·Congenital Anomalies·Masayoshi Arizawa, Masahiro Nakayama
Jan 18, 2007·Archives of Pathology & Laboratory Medicine·Zahida ParveenKaren S Thompson
Jul 20, 2007·Taiwanese Journal of Obstetrics & Gynecology·Chih-Ping Chen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.