Abstract
Early antibiotic administration has been associated with a significant decrease in infection following open fractures. However, antibiotics are most effective at a time when many patients are still being transported for care. There is limited evidence that antibiotics may be safely administered for open fractures when being transported by life-flight personnel. No such data exists for ground ambulance transport of patients with open fractures. The purpose of the study was to assess the safety and feasibility of prophylactic antibiotic delivery in the prehospital setting. We performed a prospective observational study between January 1, 2014 and May 31, 2015 of all trauma patients transferred to a level 1 trauma center by a single affiliated ground ambulance transport service. If open fracture was suspected, the patient was indicated for antibiotic prophylaxis with 2 g IV Cefazolin. Exclusion criteria included penicillin allergy, higher priority patient care tasks, and remaining transport time insufficient for administration of antibiotics. The administration of antibiotics was recorded. Patient demographics, associated injuries, priority level (1 = life threatening injury, 2 = potentially life threatening injury, 3 = non-life t...Continue Reading
References
Nov 1, 1988·Archives of Surgery·E P DellingerP A Anderson
Aug 13, 2002·Journal of Orthopaedic Trauma·Brian J HarleyDonald W Weber
May 29, 2007·Injury·D J CrowleyP V Giannoudis
Jun 23, 2007·Injury·Yassir B Al-ArabiD A Woods
Aug 12, 2009·The Canadian Journal of Cardiology·Iqbal BataUNKNOWN WEST Study Group
Jan 2, 2010·The Journal of the American Academy of Orthopaedic Surgeons·J Stuart MelvinSamir Mehta
Jan 6, 2010·The Journal of Bone and Joint Surgery. American Volume·Andrew N PollakUNKNOWN LEAP Study Group
May 26, 2011·The Journal of Trauma·William S HoffWarren C Dorlac
Jun 30, 2011·Circulation. Cardiovascular Quality and Outcomes·Seth W GlickmanChristopher B Granger
Feb 7, 2012·Annales Françaises D'anesthèsie Et De Rèanimation·A Rump
May 11, 2012·The Journal of Bone and Joint Surgery. American Volume·Mara L SchenkerSamir Mehta
Dec 5, 2012·The Journal of Trauma and Acute Care Surgery·Frank K Butler, Lorne H Blackbourne
Jan 7, 2014·Heart, Lung & Circulation·Michael L SavageDarren L Walters
Jan 1, 2015·SICOT-J·Jacques Caton, Hatem Galal Said