Preimplantation Genetic Testing: Its Evolution, Where Are We Today?

Journal of Human Reproductive Sciences
Firuza Rajesh ParikhProchi Madon

Abstract

Preimplantation genetic testing (PGT) is an early form of prenatal genetic diagnosis where abnormal embryos are identified, thereby allowing transfer of genetically normal embryos. This technology has become an integral part of Assisted Reproductive Technology (ART) procedures. Initial experiments with animals as early as 1890 and those in the mid and later part of the last century paved the forward path of ART and PGT. This review article covers the evolution of PGT and is a pointer toward current and fast-evolving technology, allowing scientists and doctors to better comprehend human reproduction, and ensure healthy pregnancy outcomes.

References

Mar 16, 2017·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org, UNKNOWN Practice Committee of the Society for Assisted Reproductive Technology

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Citations

Nov 26, 2019·Clinical Obstetrics and Gynecology·Casey L Swanson, Jamie N Bakkum-Gamez
Sep 7, 2019·Nature Reviews. Disease Primers·Olivier DevuystAnthony J Bleyer
Jan 20, 2021·Journal of Medical Ethics·Sarah Munday, Julian Savulescu
Mar 1, 2020·Journal of Gynecology Obstetrics and Human Reproduction·Farzaneh FesahatSeyed Mehdi Hoseini
Jan 1, 2020·Acta Medica Lituanica·Živilė GudlevičienėDiana Ramašauskaitė
Dec 18, 2021·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Mannie Liscum, Michael L Garcia

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Methods Mentioned

BETA
dissection
biopsy
PCR
biopsies
genotyping

Software Mentioned

PGT

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