Prelabor rupture of the membranes at term: when to induce labor?

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Y EzraNathan Rojansky

Abstract

To determine the significant predictors of clinical chorioamionitis and neonatal infection in patients with prelabor rupture of the membranes at term, and to apply this information to determination of optimal timing of labor induction. A retrospective case control series of women at > or =37 weeks' with prelabor rupture of the membranes. The study group consisted of women with evidence of maternal or neonatal infection. Controls had no evidence of infection. Three types of management were compared. (1) Immediate induction of labor, (2) expectant management up to 24 h followed by induction of labor if still necessary, or (3) expectant management for over 24 h. Univariate and multivariate analyses were performed by stepwise logistic regression (SPSS software package). The size of the study and the control groups was calculated for a 90% power with two sided P value of 0.05 in order to demonstrate an odds ratio of 2 for expectant management (two groups: early and late) versus immediate induction of labor (132 and 279 women in the study and the control groups, respectively). The rate of expectant management for over 24 h versus expectant management until 24 h followed by induction of labor when still necessary, was higher among cas...Continue Reading

References

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Citations

Oct 22, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ashraf F NabhanMohamed Elkadi
Oct 29, 2011·Neurologic Clinics·Peter W Kaplan
Oct 30, 2014·The Cochrane Database of Systematic Reviews·Aleena M WojcieszekVicki Flenady
Feb 22, 2014·Journal of Assisted Reproduction and Genetics·Richard T ScottKathleen M Upham
Dec 13, 2007·American Journal of Physiology. Endocrinology and Metabolism·Sarah L WakefieldMegan Mitchell
Nov 22, 2013·Journal of Perinatal Medicine·Armando PintucciAngelo Fiorilli

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