Preliminary experience with air transfer of patients for rescue endovascular therapy after failure of intravenous tissue plasminogen activator

Neurologia Medico-chirurgica
Masanori TsujimotoToru Iwama

Abstract

The present report describes our experience with air transfer of patients with acute ischemic stroke in whom intravenous tissue plasminogen activator (IV t-PA) failed for rescue endovascular therapy (EVT). Twenty-three consecutive patients in whom IV t-PA failed were transferred to our hospital for rescue EVT between February 2011 and April 2013. The amount of time required for transfer, distance, clinical outcomes, and complications were compared between patients transferred by ground (TG group; n = 17) and by air (TA group; n = 6). Computed tomography imaging on arrival revealed hemorrhagic transformation in 1 (5.9%) patient in the TG group, whereas none of the patients in the TA group developed any type of complication. The remaining 22 patients received rescue EVT. The elapsed time from the request call to arrival at our hospital did not significantly differ between the TG and TA groups (45.8 ± 4.9 min vs. 41.6 ± 2.3 min). However, the distance from the primary hospital to our institution was significantly longer for the TA group than for the TG group (38.8 ± 10.4 km vs. 13.5 ± 1.2 km, p = 0.001). The frequency of favorable outcomes (modified Rankin Scale 0-1 at 90 days after onset) in the TG and TA groups were 25.0% and 50...Continue Reading

References

Dec 14, 1995·The New England Journal of Medicine·UNKNOWN National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
Nov 5, 1999·Stroke; a Journal of Cerebral Circulation·J A ChalelaA M Pancioli
Feb 3, 2007·Stroke; a Journal of Cerebral Circulation·Joung-Ho Rha, Jeffrey L Saver
Feb 10, 2007·Stroke; a Journal of Cerebral Circulation·Maher SaqqurUNKNOWN CLOTBUST Investigators
May 26, 2007·Stroke; a Journal of Cerebral Circulation·UNKNOWN IMS II Trial Investigators
Mar 1, 2008·Stroke; a Journal of Cerebral Circulation·Wade S SmithIsaac E Silverman
Sep 26, 2008·The New England Journal of Medicine·Werner HackeUNKNOWN ECASS Investigators
Sep 30, 2009·Neurology·P KhatriUNKNOWN IMS I and II Investigators
Feb 13, 2010·Stroke; a Journal of Cerebral Circulation·Thomas PfefferkornGunther Fesl
Mar 31, 2010·Neurology·T A TomsickUNKNOWN IMS III Executive Committee
Sep 21, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Silvina B TonarelliAdnan I Qureshi
Mar 29, 2011·Stroke; a Journal of Cerebral Circulation·Veronika Reiner-DeitemyerUNKNOWN Austrian Stroke Unit Registry Collaborators
May 12, 2011·International Journal of Stroke : Official Journal of the International Stroke Society·Alfonso CicconeUNKNOWN SYNTHESIS Expansion investigators
Feb 8, 2013·The New England Journal of Medicine·Alfonso CicconeUNKNOWN SYNTHESIS Expansion Investigators
Feb 9, 2013·The New England Journal of Medicine·Joseph P BroderickUNKNOWN Interventional Management of Stroke (IMS) III Investigators
Feb 12, 2013·The New England Journal of Medicine·Chelsea S KidwellUNKNOWN MR RESCUE Investigators
Jan 16, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Shinichi YoshimuraUNKNOWN Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan Registry Investigators

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Citations

Feb 20, 2019·Stroke; a Journal of Cerebral Circulation·Paula M JanssenDiederik W J Dippel

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