Preliminary experience with triamcinolone acetonide during pregnancy

The Journal of Maternal-fetal Medicine
M P DombrowskiS M Berry

Abstract

Although inhaled corticosteroids have been recommended, there are no published reports of triamcinolone acetonide therapy for asthma during pregnancy. The objective of this study was to report our experience with triamcinolone acetonide during pregnancy. This was a retrospective cohort study in a tertiary care urban hospital. We compared birth weights and the proportion of subjects hospitalized for asthma exacerbations among pregnant women receiving inhaled triamcinolone acetonide, inhaled beclomethasone dipropionate, and oral theophylline. The mean triamcinolone acetonide group (n = 15) birth weight was 502 g more than the beclomethasone group (n = 14) and 316 g more than the theophylline group (n = 25); however, these differences were not statistically significantly. Fewer patients treated with triamcinolone acetonide (n = 5, 33%) required hospital admissions for asthma exacerbations compared to those treated with beclomethasone (n = 11, 79%; P < 0.05) but not theophylline (n = 7, 28%; P = NS). Our preliminary data suggest that triamcinolone acetonide appears to be at least as efficacious for the treatment of asthma during pregnancy as is beclomethasone. These results should be confirmed by a clinical trial to further evaluat...Continue Reading

Citations

Apr 29, 2005·Journal of Women's Health·Scott L Osur
Jun 30, 2011·The Annals of Pharmacotherapy·Angelina LimJohnson George
Sep 25, 2004·Critical Care Clinics·Elizabeth S GuyNicola A Hanania
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Thomas R Flynn, Srinivas M Susarla

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

The Journal of Allergy and Clinical Immunology
Andrea J Apter
The Journal of Allergy and Clinical Immunology
M P DombrowskiDonald McNellis
Thorax
B Stenius-AarnialaK Teramo
American Journal of Respiratory and Critical Care Medicine
R K CydulkaC A Camargo
© 2021 Meta ULC. All rights reserved