Preliminary feasibility study of an in-line phase contrast X-ray imaging prototype

IEEE Transactions on Bio-medical Engineering
Da ZhangHong Liu

Abstract

In this study, a series of imaging experiments on biological specimens, including human breast core biopsies, lumpectomy, and chicken tissues, as well as standard phantoms, were performed in an effort to investigate the feasibility of an in-line phase contrast X-ray imaging prototype. The prototype system employed in the study consists of a microfocus X-ray source with tungsten target and a digital flat panel detector, and it can be operated in both conventional attenuation-based imaging mode and in-line phase contrast imaging mode. Biological specimens were imaged in the conventional mode and phase contrast mode with the same source-to-image-detector distance (SID), and phase contrast images exhibited both improved image quality compared with conventional images, and the overshooting patterns along the boundaries in the specimens, which revealed the occurrence of the edge enhancement effect provided by the phase contrast technique. In addition, the performance of the phase contrast mode and conventional mode was compared based on the American College of Radiology (ACR) phantom imaging and contrast detail mammography (CDMAM) phantom-based contrast detail analysis with two experimental settings: one with the same SID and the oth...Continue Reading

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Citations

Dec 25, 2012·International Journal of Computer Assisted Radiology and Surgery·Akiko IhoriYoshie Kodera
May 29, 2014·Journal of X-ray Science and Technology·Molly Donovan WongHong Liu
Sep 22, 2018·Microscopy Research and Technique·Huiqiang LiuWenya Liu
Jun 25, 2009·Optics Express·Xizeng Wu, Aimin Yan
Nov 21, 2017·Journal of X-ray Science and Technology·Liqiang RenHong Liu
Jul 31, 2013·Journal of Instrumentation : an IOP and SISSA Journal·A YanH Liu
Jul 21, 2015·Applied Optics·Huiqiang LiuTiqiao Xiao
Jan 1, 2020·Biomedical Spectroscopy and Imaging·F H OmoumiH Liu

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