PMID: 7547180Feb 1, 1995Paper

Preliminary observations of transverse relaxation rates obtained at 3 tesla from the substantia nigra of adult normal human brain

NMR in Biomedicine
J A HelpernK M Welch

Abstract

The transverse relaxation rates R2 and R2* were measured at 3 T in the substantia nigra of the midbrain of adult normal human controls. The relaxation rate arising from magnetic inhomogeneities, R2', was calculated from the relationship R2* = R2 + R2'. No significant differences were found for any parameters between left and right side substantia nigra regions, however, a significant inverse correlation was found between R2 and R2' (r = 0.70, p = 0.035). Water diffusion, in the presence of paramagnetic metal ions, may play a role in determining the relative contributions to reversible and irreversible transverse relaxation and may explain the inverse correlation demonstrated here.

References

Sep 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R J OrdidgeJ A Helpern

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Citations

May 8, 1999·Journal of Magnetic Resonance Imaging : JMRI·J P WansapuraW S Ball
Nov 20, 2013·Mathematical Biosciences and Engineering : MBE·Juan Pablo AparicioJorge Eduardo Rabinovich
May 18, 2005·Neurochemical Research·Maria F FalangolaJoseph A Helpern

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